In turn, these exchanges create several types of communities with their own interaction dynamics, rules, and vocabulary (Taylor & Jackson, 2018), called “sub-reddits” hosted within Reddit. This work was conducted using posts (threads) from the subreddits NoFap (see r/NoFap) and Pornfree...
HEALTH care reformOLDER peopleObjective: The Pathways to Community Living Initiative (PCLI) aims to reform mental health care for people with severe and persistent mental illness (SPMI) and complex needs. This study reports independent evaluation findings on transitions from hospital and practice ...
5xFAD mice and age-matched control wild-type littermates were obtained from the Jackson Laboratory (wild type: C57BL/6 J 000664; 5xFAD: C57BL/6 J 5xFAD 034848). Cerebral cortex and hippocampus were collected at 5 and 7 months of age. All animal procedures and protocols were approved by...
13. Ligand-dependent bias has important implications for drug development and clinical pharmacology14,15. For example, the G protein-biased μ-opioid receptor (MOR) agonist oliceridine reportedly has a correspondingly improved tolerability profile16, although alternative explanations...
BTBR (stock # 002282),Fmr1-KO (stock # 003025) and C57BL/6 J (stock # 000664) mice were purchased from Jackson Laboratory (Bar Harbor, ME) and were housed in a facility accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care. All mice were kept und...
Jackson, Xueling Sim & Heather M. Stringham McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA Adam E. Locke William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK Eirini Marou...
Hashimoto T, Tayama M, Miyazaki M, Yoneda Y, Yoshimoto T, Harada M, Miyoshi H, Tanouchi M, Kuroda Y (1995) Reduced-acetylaspartate in the brain observed on in vivo proton magnetic resonance spectroscopy in patients with mental retardation. Ped Neurol 13:205–208 ...
84. Liu S, Dontu G, Mantle ID, Patel S, Ahn NS, Jackson KW, Suri P, Wicha MS. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res. 2006;66(12):6063–71. 85. Choi HS, Kim SL, Kim JH, Lee DS. The FDA-approved ...
More generally, meta-analyses have shown that regular physical activity improves both mental health and physical health in terms of blood pressure and chronic disease (breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events) [168,169,170]. Thirdly, through an ...
Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA James G. Wilson Danish Diabetes Academy, Odense, Denmark Daniel R. Witte Department of Public Health, Aarhus University, Aarhus, Denmark Daniel R. Witte GlaxoSmithKline, King of Prussia, PA, USA Lau...