Given the flexibility of this approach, we believe it provides another means in which the roles of pathways in drug response for cancers can be evaluated and to provide another steppingstone towards cancer precision medicine. Methods Data Drug sensitivity data, cell-line gene expression, somatic ...
Network effects, economies of scale, and lock-in-effects increasingly lead to a concentration of digital resources and capabilities, hindering the free and equitable development of digital entrepreneurship, new skills, and jobs, especially in small commu
The aryl hydrocarbon receptor (AHR) is a transcription factor that is commonly upregulated in pancreatic ductal adenocarcinoma (PDAC). AHR hinders the shuttling of human antigen R (ELAVL1) from the nucleus to the cytoplasm, where it stabilises its target