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Given the flexibility of this approach, we believe it provides another means in which the roles of pathways in drug response for cancers can be evaluated and to provide another steppingstone towards cancer precision medicine. Methods Data Drug sensitivity data, cell-line gene expression, somatic ...
A stepping-stone toward replicating in vivo cues in in vitro tissue models is the integration of vasculature at physiological scales within 3D cell-laden hydrogel cultures for precisely delivering spatiotemporal chemical, mechanical, and mass transport cues. This obstacle is addressed by presenting a ...
Both AHR and ELAVL1 are involved in the immune system of the body. This poses a limitation to in vitro experiments due to absence of immune cells. Nonetheless, this novel mechanism provides a stepping stone for combating gemcitabine resistance in PC and should be investigated in in vivo setting...
which will operate under stringent neutrality requirements, thereby offering a stepping stone towards our recommended structure of data cooperatives. However, the Act lacks explicit support for cooperative models and does not offer specific mechanisms to foster trust and engagement from data subjects, elem...