4G). These data suggest that these five mRNAs, which had been shown to be direct targets of miR-34b/c, can also be directly regulated by miR-449a in vitro. Exhaustive Correlation Analysis of Genome-wide mRNA Transcriptomic Changes Induced by miR-449a/b or miR-34b/c To further ...
4g). These results suggested that DGG-100629-induced DDIAS downregulation was required for the suppression of STAT3 activation and the promotion of apoptosis in NSCLC cells. DGG-100629 inhibited tumor growth in a mouse xenograft model To investigate the effect of DGG-100629 on tumor growth, a ...
4g) as well as association with disease-specific survival and PFI (Fig. 4h, i), the same dataset was used and filtered for “TCGA” tumors. “Normal” as well as “control” samples were removed. For the association of SLC35B2 expression and melanoma outcome (Fig. 4j), the TCGA ...
4G, epithelial cells, monocyte-like cells, M1 and M2 macrophages demonstrated stronger MDK-LRP1/SORL1 interactions in cancers with ErbB mutations than in those without ErbB mutations. Indeed, a considerable number of the MDK-related receptor mutations were accumulated in GBC2 and GBC7 (Fig. S11...
It also indicated that the level of phospho-AKT, 4EBP1, and eIF4E increased along with the expression of PHLPP2 (Figure 4G-4H). Consistently, to assess whether mutant p53 can directly regulate PHLPP2 in cancer cells, we firstly presume that mutant p53 may bind to the promoter of PHLPP2....
Initiation factor eIF4G is an essential protein required for initiation of mRNA translation via the 5' cap-dependent pathway. It interacts with eIF4E (the mRNA 5' cap-binding protein) and serves as an anchor for the assembly of further initiation factors. With treatment of Saccharomyces cerevisiae...
03015 mRNA surveillance pathway 20 492 114 3857 0.082844862 1.375338753 "[FvH4_7g29390, FvH4_6g17300, FvH4_5g13570, FvH4_3g29340, FvH4_4g03530, FvH4_2g38640, FvH4_1g18700, FvH4_1g18000, FvH4_2g34040, FvH4_5g33710, FvH4_6g06810, FvH4_5g25490, FvH4_5g03260, FvH4_...
这一概念与以下观点一致:Tshz1+dMSN编码气喘的价值(图4F和4G;图S4F和S4G),并且在执行/不执行任务时厌恶性学习需要Tshz1+dMSN的活动(图7;图S7)。另一方面,成功细胞可以表示未来惩罚的预期价值,因此有助于在预期惩罚时避免回避。此功能类似于先前描述的"负动机"或"平均显著性"。ND细胞可能在评估和振奋功能...
S4G-I). i The α-WDR41-SC antibody does not detect endogenous protein in SGs of NaAsO2-stressed 2102Ep cells. NT: no treatment. Cell nuclei were stained with Hoechst 33342 (right-most panels). Size bars are 10 μm Full size image Thus, SMCR8 protein is bound by ubiquitin and ...
Zhang K, Cui S, Chang S, Zhang L, Wang J: i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study. Nucleic Acids Res. 2010, 38: W90-95. 10.1093/nar/gkq324. Article...