This chapter reviews the etiopathogenesis of type 1 diabetes, which includes genetic (such as a strong association with HLA haplotypes, genetic linkage with immune system genes), immunological (such as specificity for beta cells and the presence of antigen-specific T cells), environmental factors (s...
I.13 Pathophysiology of Type 1 diabetes mellitus The nature of the genetic influence in the pathogenesis of type 1 diabetes is unclear in that nowwe have many forms of exercise, be they CrossFit, endurance, powerlifting In the study, bothaerobic exercises and resistance exercise were......
Type 1 diabetesCellular microenvironmentsIsletsOrganoid-on-a-chipIsogenic cellular systemsBiomimetic modelingThe pathophysiology of type 1 diabetes is a complex process involving tightly controlled microenvironments, a number of highly specific immune cell - islet cell interactions, and the eventual breaking...
Pathophysiology of Facial Nerve Paralysis Induced by Herpes Simplex Virus Type 1 Infection Herpes simplex virus type 1 (HSV-1) has been proven to be a cause of Bell's palsy; however, the underlying pathophysiology of the facial nerve paralysis is... H Kisaki,N Honda,H Takahashi,... - 《...
Following the pathological delamination of the dural border cells, two membranes are formed, enclosing the new subdural cavity which fills with the fluid and blood. High concentrations of type 1 (PICP) and type 3 (PIIINP) procollagen are present in this fluid and suggest a fibro-proliferative ...
The state of intermediate hyperglycemia is indicative of elevated risk of developing type 2 diabetes1. However, the current definition of prediabetes neither reflects subphenotypes of pathophysiology of type 2 diabetes nor is predictive of future metabol
The Role of Type 1 and Type 2 5\"-Deiodinase in the Pathophysiology of the 3,5,3\"-Triiodothyronine Toxicosis of McCune-Albright Syndrome Eugster,E. - 《Yearbook of Endocrinology》 被引量: 0发表: 2008年 The effect of 3,5,3'-triiodothyronine supplementation on zebrafish (Danio rerio) ...
Nutritional deficiencies are commonplace in patients with human immunodeficiency virus type 1 (HIV-1) infection, and recent research has indicated that nutritional factors may play an important role in the pathogenesis of HIV-1 disease. Although nutritional deficiencies are unlikely to be the primary ...
The pathophysiology of acute illness and injury recognizes three main effectors: infection, trauma, and ischemia-reperfusion injury. Each of them can act by itself or in combination with the other two in developing a systemic inflammatory reaction syndrome (SIRS) that is a generalized reaction to ...
Type 2 diabetes mellitus (DM) is characterized by insulin resistance and pancreatic beta cell dysfunction. In high-risk subjects, the earliest detectable a... ME Patti,AJ Butte,S Crunkhorn,... - 《Proceedings of the National Academy of Sciences》 被引量: 2884发表: 2003年 Activation of PPAR...