R. et al. Elevated cardiac troponin I in sepsis and septic shock: no evidence for thrombus associated myocardial necrosis. PLoS ONE 5, e9017 (2010). PubMed PubMed Central Google Scholar Solomon, M. A. et al. Myocardial energy metabolism and morphology in a canine model of sepsis. Am....
Within the first 72 hours of hospital admission for TTC, cardiogenic shock occurs in 11% of hospitalized patients, and 20% to 25% present with left ventricular outflow tract obstruction (LVOTO) [63]. Positive inotropic agents (eg, dopamine/dobutamine) are preferred over sympathomimetic cholinergic...
(NSTEMI) are associated with atherosclerotic plaque fissuring or ulceration, adherence of platelets at the same sites, the accumulation of thromboxane A2, serotonin, adenosine diphosphate (ADP), thrombin, tissue factor, oxygen-derived free radicals, and endothelin promoting growth of the thrombus and...
Proximal occlusion of the left anterior descending artery (LAD) (A) (arrow). After introduction of the first guidewire, intraluminal thrombus (haziness) at the bifurcation of LAD (arrow)and second diagonal branch (*)can be seen (B). After thrombosuction and stenting followed by kissing balloon...
The vascular response to hypoxia is controlled by hypoxia-inducible transcription factors (HIF), facilitated by thrombus formation, leading to blood clots [202]. In other words, antiphospholipid antibodies (produced from immune cells) cause severe tissue damage due to coagulation [203]. Besides, the...
formation of thrombus. In addition, foam cells necrosis and other inflammatory cells build up the necrotic core. While efferocytosis prevents inflammation and plaque growth, the impaired efferocytosis of apoptotic/necrotic bodies may lead to further deposition of macrophages/foam cells in the plaque. ...
After adhesion to the endothelium (white thrombus formation), platelets enhances the inflammatory and coagulation cascade by expression of TF on activated monocytes and endothelial cells [222]. Clinical conditions associated with overt DIC are summarized in Table 2.3. Table 2.3 Clinical pictures often ...
Altmann, D. R. et al. Elevated cardiac troponin I in sepsis and septic shock: no evidence for thrombus associated myocardial necrosis.PLoS ONE5, e9017 (2010). PubMedPubMed CentralGoogle Scholar Solomon, M. A. et al. Myocardial energy metabolism and morphology in a canine model of sepsis....
of the disease is the increased propensity for thrombus formation and this procoagulant phenotype in APS occurs as a result of the synergy of many contributory elements. These include aPL-mediated activation of platelets, monocytes, and endothelial cells and aPL-induced perturbation of natural ...
In patients with kidney disease, nephrotic syndrome can lead to several complications including progressive kidney dysfunction. Proteinuria may lead to the