A hypothesis is presented suggesting that the pathogenesis of apical lung disease is due to progression of subclinical congenital apical bullae in people with low Body Mass Index (BMI), a combination present in 15% of the population, due to high pleural stress levels present in the antero-...
Mechanotransduction determines the structure and function of lung and bone: a theoretical model for the pathophysiology of chronic disease. Multicellular organisms have evolved in adaptation to the Earth's gravitational and oxygen environment. This epigenetic process is dependent on the capacit... JS Tor...
Production of ACTH by nonpituitary tumors can also result in hypercortisolism. These tumors are frequently malignant and account for approximately 10% of cases of CS. The hypercortisolism of ectopic ACTH syndrome can precede a cancer diagnosis by many years and include lung, thyroid, gastrointestin...
Influence of distinct asthma phenotypes on lung function following weight loss in the obese Background and objective There appears to be two distinct clinical phenotypes of obese patients with asthma—those with early-onset asthma and high serum I... DG Chapman,CG Irvin,DA Kaminsky,... - 《Res...
The classification of the nervous system and the summary of peripheral nervous system (PNS).AClassification of the nervous system.BSummary of efferent pathways in the PNS. The autonomic nervous system is organized in three anatomical and biochemical distinct systems, the sympathetic nervous system (SN...
Pulmonary artery pressure PCI: Percutaneous coronary intervention PoPH: Portopulmonary hypertension SVR: Systemic vascular resistance TIPS: Transjugular porto-systemic shunt TLC: Total lung capacity TNF: Tumour necrosis factor VEGF: Vascular endothelial growth factor vWF: Von Willebrand factor ...
Left atrial (LA) pressures rise, and pulmonary venous congestion ensues, causing hydrostatic pressures in the lung to rise dramatically. This rise in hydrostatic pressures causes capillary leak and subsequent pulmonary edema. This edema causes alveolar collapse and results in decreased ventilation, which...
weeks' gestation. Before this, the patient is usually hospitalized and monitored carefully for the development of worsening preeclampsia or complications of preeclampsia, and the immature fetus is treated with expectant management with corticosteroids to accelerate lung maturity in preparation for early ...
Owens GK, Schwartz SM. Alterations in vascular smooth muscle mass in the spontaneously hypertensive rat. Role of cellular hypertrophy, hyperploidy, and hyperplasia.Circ Res1982;51:280–289. ArticlePubMedCASGoogle Scholar Berk BC. Biology of the vascular wall in hypertension. In Brenner and Rector...
Wolin MS, Ahmad M, Gupte SA. Oxidant and redox signaling in vascular oxygen sensing mechanisms: basic concepts, current controversies, and potential importance of cytosolic NADPH. Am J Physiol Lung Cell Mol Physiol. 2005;289(2):L159–73. ...