embolization,cyst fenestration,hepatic resection and liver transplantation are indicated to specific groups of patients and have to be tailored according to the extent of disease.This review outlines the current knowledge of the pathophysiology,clinical course,diagnosis and treatment strategies of PLD.世界...
A 36-year-old male developed asymmetric polyarthritis during the course of hydatid disease of the liver. Excision of the hydatid cyst was accompanied by fu... MB Yunus - 《Journal of Rheumatology》 被引量: 623发表: 1992年 Narrative review: The pathophysiology of fibromyalgia Primary fibromyalgia...
The term hepatic cyst usually refers to solitary nonparasitic cysts of the liver, also known as simple cysts. However, several other cystic lesions must be distinguished from true simple cysts. Cystic lesions of the liver include the following: Simple cysts Multiple cysts arising in the setting...
Currently, the only available drug treatments that halt disease progression and improve quality of life in PLD patients are somatostatin analogues. Numerous preclinical studies suggest that targeting components of the signaling pathways that influence cyst development can ameliorate growth of hepatic cysts....
Functional changes in the structure and function of these complexes can occur if any of the individual protein components are altered. Mutations that modify cystoprotein complexes ultimately result in aberrant integration of complex signaling events and PKD. Cyst initiation and expansion is a complex ...
which suggests that SIRT1 may act as a critical modulator of systemic oxygen levels and local oxygen tension.84 SIRT1 stimulates the activity of the liver-X receptor (LXR)85 and the farnesoid X receptor (FXR),86 both of which regulate lipid metabolism.85,86 SIRT1 activated-LXR and -FXR ...
Women also experience localized peritonitis from an infected fallopian tube or a ruptured ovarian cyst. Patients may present with an acute or insidious onset of symptoms, limited and mild disease, or systemic and severe disease with septic shock. (See Etiology.) Peritoneal infections are classified ...
Hiramatsu K, Paye F, Kianmanesh AR, Sauvanet A, Terris B, Belghiti J (2001) Choledochal cyst and benign stenosis of the main pancreatic duct. J Hepatobiliary Pancreat Surg 8:92–94 Hogan WJ, Geenen JE (1988) Biliary dyskinesia. Endoscopy 20 (Suppl 1):179–183 Howes N, Greenhalf W...
In this review, we summarize the NET-mediated pathophysiology of different diseases and focus on some updated potential therapeutic approaches against NETs. Keywords: neutrophil extracellular traps (NETs); innate immunity; sepsis; lung disease; cardiovascular disease; liver disease; kidney disease; ...
The main cause of the cytopenia, splenomegaly, hepatomegaly, and bone lesions associated with the disease is considered to be the infiltration of the bone marrow, spleen, and liver by Gaucher cells. Type-1 Gaucher disease, which affects the majority of patients (90% in Europe and USA, but...