Musculoskeletal: Possible arthritis and arthralgia, particularly of the large joints [6] Dermatologic: May show pallor or jaundice, mucocutaneous or aphthous ulcers, erythema nodosum, and pyoderma gangrenosum Ophthalmologic: May reveal episcleritis; possible uveitis Growth delay: Decreased growth veloci...
ERYTHEMA nodosumANKYLOSING spondylitisThe inflammatory bowel diseases (IBDs) are systemic conditions that affect not only the gastrointestinal tract but also other parts of the body. The presence of extraintestinal manifestations can significantly impact the quality of life in IBD...
Erythema multiforme (EM), including EM minor, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap Erythema nodosum Erythroderma Fixed drug eruptions Hypersensitivity syndrome Leukocytoclastic vasculitis Lichenoid Lupus Morbilliform or exanthematous Pseudoporphy...
discontinuation of multi-kinase inhibitor (MKIs), imatinib therapy due to TKI-associated adverse effects.10Toxicity can be attributed to bothon-targeteffects through excessive inhibition of the intended TK function; and/oroff-targeteffects resulting from the simultaneous inhibition of multiple other kinas...
Erythema nodosum A lower-extremity panniculitis with painful, erythematous nodules (often with Löfgren syndrome) Lupus pernio (the most specific associated cutaneous lesion) Violaceous rash on the cheeks or nose (common) Maculopapular plaques (uncommon) Ocular involvement, which may lead to...
Yersinia infection: Erythema nodosum, exudative pharyngitis Vibrio vulnificus or V alginolyticus infection: cellulitis, otitis media Always perform a rectal examination to (1) directly visualize the stool, (2) test occult blood, and (3) palpate the rectal mucosa for any lesions. Testing The foll...