Rodent diabetic models, used to understand the pathophysiology of diabetic cardiomyopathy (DCM), remain several limitations. Engineered cardiac tissues (ECTs) have emerged as robust 3D in vitro models to investigate structure-function relationships as well as cardiac injury and repair. Advanced glycation...
What is the pathophysiology of Alzheimer's disease? What is the pathophysiology of Guillain-Barre syndrome? What is the main electrolyte involved in cardiomyopathy? What is idiopathic cardiomyopathy? What is the pathophysiology of osteoporosis?
“Cardiomyocyte hypertrophy” in diabetic cardiomyopathy is referred to in some earlier reviews, but its contribution to “ventricular hypertrophy” is not clear. Human myocardium biopsied at the time of coronary bypass surgery showed an increased cross-sectional area (CSA) of cardiomyocytes and intersti...
What is diabetic cardiomyopathy? What is the pathophysiology of coronary artery disease? What are viral cardiomyopathy symptoms? What is cardiac etiology? What are the symptoms of hypertrophic cardiomyopathy? What is the pathophysiology of pancreatitis?
Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 1994; 331: 1480–1487. Google Scholar Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N . Vascular endothelial growth factor is a secreted angiogenic mitogen...
Colao, A. et al. Systemic hypertension and impaired glucose tolerance are independently correlated to the severity of the acromegalic cardiomyopathy.J. Clin. Endocrinol. Metab.85 Vila, G. et al. Hypertension in acromegaly in relationship to biochemical control and mortality: global ACROSTUDY outcomes...
Additionally, retrospective studies, as well as small studies with the number of patients below 100, and animal studies were also included. The main data search terms were: diabetes mellitus, HF, diabetic cardiomyopathy, clinical studies, clinical trials, metabolic disturbances, m...
The potential role of undercarboxylated osteocalcin upregulation in microvascular insufficiency in a rat model of diabetic cardiomyopathy Journal of Cardiovascular Pharmacology and Therapeutics (2019), Article 1074248419876632 Google Scholar [58] L. Huang, L. Yang, L. Luo, P. Wu, S. Yan Osteocalcin...
Farhangkhoee H, Khan ZA, Kaur H et al (2006) Vascular endothelial dysfunction in diabetic cardiomyopathy: pathogenesis and potential treatment targets. Pharmacol Ther 111(2):384–399 Asbun J, Villareal FJ (2006) The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy. J...
pathogenesis of primary hypertension via impaired degradation of ANG II, and reduced formation of vasodilator by-products at the level of the renal endothelium (41). Alterations in ACE2 activity have also been shown to have a potential role in the development of diabetic nephropathy in animal ...