Androgen deprivation therapy (ADT) is the foundation of systemic therapy for prostate cancer. Although it is an effective cancer treatment in a variety of clinical settings, it causes accelerated loss of bone mineral density (BMD) and is associated with an increased incidence of fractures. National...
Prostate cancer is more common in the western countries, least common in Asia, and the leading cause of cancer deaths in males worldwide. Individuals who have first-degree family members with prostate cancer have double the risk of getting disease. Risk factors for prostate cancer include family...
Several studies have attempted to correlate the extent of skeletal metastatic involvement, the number of bone metastases (BMTs) identified by bone scintigraphy or the distribution of BMTs (axial vs appendicular) with survival in patients with advanced prostate cancer (PC) [1, 2]. The number of ...
Novel molecular targets for the therapy of castration-resistant prostate cancer. Improved understanding of mechanisms underlying metastatic castration-resistant prostate cancer (mCRPC) progression has led to the recognition of multiple ... N Agarwal,G Sonpavde,CN Sternberg - 《European Urology》 被引量...
These mechanisms of spread make prostate cancer an interesting experimental model to study the pathogenesis and molecular basis of bone metastatic disease, which may ultimately provide a new insight for novel treatment strategies. 展开 出版时间: 2010 ...
et al. Multimodality treatment of gynecomastia in patients receiving antiandrogen therapy for prostate cancer in the era of abiraterone acetate and new antiandrogen molecules. Oncology 84, 92–99 (2013). CAS PubMed Google Scholar Evans, D. L., Pantanowitz, L., Dezube, B. J. & Aboulafia...
Bone is a very common site for cancer metastasis and may be the only site of metastasis in patients with breast cancer or prostate cancer. The exact incidence of bone metastasis is unknown, but it has been estimated that approximately 300,000–400,000 people in the United States die from bo...
Bone Cancer, 2nd Edition comprehensively investigates key discoveries in the field of bone biology over the last five years that have led to the development of entirely new areas for investigation, such as therapies which combine surgery... Heymann 被引量: 15发表: 2014年 Cancer Pain: The assess...
Xenotropic murine leukemia virus–related virus (XMRV) is a new human retrovirus originally identified in prostate cancer patients with a deficiency i
p>Parathyroid hormone-related protein (PTH-rP) was purified and cloned 10 years ago as a factor responsible for the hypercalcemia associated with malignanc... TA Guise - 《Cancer》 被引量: 1211发表: 1997年 Parathyroid hormone: past and present Research on parathyroid hormone (PTH) has undergon...