These antibodies are predominantly of the IgA class, however some other classes of antibodies may also be produced.3,16 An inflammatory infiltrate, composed of neu- trophils, can be found in skin lesions of DH patients, usually in the papillary dermis, the same place where IgA depo...
The second goal of the article is to outline the therapeutic implications of peroxynitrite, and to give an overview of the various pharmacological classes of peroxynitrite scavengers and peroxynitrite decomposition catalysts. Peroxynitrite induces cell death, and can influence signal-transduction processes, ...
72 Targeting the Virus and the Host Response The following classes of drugs are being evaluated or developed for the management of COVID-19: antivirals (eg, remdesivir, favipiravir), antibodies (eg, convalescent plasma, hyperimmune immunoglobulins), anti-inflammatory agents (dexamethasone, statins),...
M. et al. Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells. Mol. Cell. Biol. 12, 240–247 (1992). CAS PubMed PubMed Central Google Scholar Schlessinger, J. et al. Crystal structure of a ternary FGF...
Methods: This quasi-experimental study was conducted at a single LCME-accredited medical school and included a convenience sample from 2 consecutive classes of medical students during the musculoskeletal portion of their physical diagnosis class. We conducted a needs assessment of the traditional ...
Bipolar disorder (BPD) is characterized by recurrent episodes of disturbed affect including mania and depression as well as changes in psychovegetative function, cognitive performance, and general health. A growing body of data suggests that BPD arises f
This quasi-experimental study was conducted at a single LCME-accredited medical school and included a convenience sample from 2 consecutive classes of medical students during the musculoskeletal portion of their physical diagnosis class. We conducted a needs assessment of the traditional curriculum used ...
Prostate cancer is the second most frequently occurring cancer diagnosed among males. Recent preclinical evidence implicates cannabinoids as powerful regulators of cell growth and differentiation. In this review, we focused on studies that demonstrated a
In the last few years, new pharmacological classes with antihypertensive actions have also demonstrated significant efficacy in the treatment of HF, such as SGLT2i and new non-steroidal MRA. On the other hand, other proposed agents, such as ET-1 receptor antagonists, have provided contrasting ...
There is an ever-growing urgency to diagnose IE and its complications, and to institute the most appropriate antibiotic treatment. The increasing resistance to the "tried and true" empiric regimens is becoming untenable because of the wide development of resistance to multiple classes of agents. Thi...