Female transgenic mice with five familial AD mutations (5XFAD, mixed b6/SJL background) were purchased from Jackson Lab (Bar harbor, ME, USA). These mice co-express and co-inherit FAD mutant forms of human APP (the Swedish mutation: K670N, M671L; the Florida mutation: I716V, and ...
The other study was performed in a vascular biology lab (Armulik et al., 2010) and addressed the function of pericytes in the adult mouse. Both studies independently concluded that pericyte deficiency caused increased brain vessel permeability, the extent of which correlated directly with the ...
Cai D, Iyer A, Felekkis KN, Near RI, Luo Z, Chernoff J, Albanese C, Pestell RG, Lerner A (2003) AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter. Cancer Res 63:6802–6808 CASPubMedGoogle Schol...
Thus, directly designing a device might not be the recommended method for successful lab-on-a-chip development. In this paper, we have tried to highlight many of the diseases that are common and rampant in the world. Addressing them and quickly setting up labs or equipment is a must. To...
Stenirri, S.; Santambrogio, P.; Setaccioli, M.; Erba, B.G.; Manitto, M.P.; Rovida, E.; Ferrari, M.; Levi, S.; Cremonesi, L. Study of FTMT and ABCA4 genes in a patient affected by age-related macular degeneration: Identification and analysis of new mutations.Clin. Chem. Lab....
For miRNA analysis, cDNA conversion was performed with the universal cDNA Synthesis Kit (Qiagen, Hilden, Germany), as usual in our lab [34], using 5 ng total RNA according to the following protocol: 60 min at 42 ◦C followed by heat inactivation of the reverse transcriptase for 5 min ...