The fatty streak, which is a yellow, generally flat patch on the intima made up of accumulated lipid-containing smooth muscle cells. Commonly found in young individuals fatty streaks probably have no pathological significance in many cases. 2. The fibrous plaque, which is an intimai deposit of...
It has been revealed that anemia in patients with CVD (cardiovascular diseases) is not only associated with unfavorable prognosis, but also becomes a marker of peculiarities in mechanism of disease development indicating the severity of inflammatory componentSuvorova S.A...
Coronary (artery) spasm plays an important role in the pathogenesis of ischemic heart disease, including stable angina, unstable angina, myocardial infarction, and sudden death. The prevalence of coronary spasm differs among populations, is higher in Japan and Korea than in the Western countries prob...
Influenza A virus NS1 suppresses nuclear speckles promoted gene expression by inhibition of transcription Wolfgang Nacken Juliane Mayr Stephan Ludwig ResearchOpen Access30 May 2025npj Viruses Volume: 3, P: 46 Understanding of the characteristics of fibroblasts in ischemic cardiomyopathy using single-nucleus...
Since 1974 ischemic heart diseases have accounted for approximately 65% of all cardiovascular diseases and were responsible for every third death in the United States during this period. The purported increase in the incidence of ischemic heart disease in civilized communities during the first two ...
32, 33, 34, 35 The importance of cardiovascular disease in HIV-infected people receiving highly active antiretroviral therapy has been underscored by the reported increased risk of ischemic heart disease in this group as compared with the general uninfected population.36 A number of mechanisms ...
Ischemic stroke is a common neurological disease with the characteristics of high morbidity, high mortality and high recurrence, and its pathogenesis has been one of the hot spots of research. In recent years, with the continuous development of neuroscience and biomedical research methods, a lot of...
[9]. In contrast, loss-of-function experiments suggested that tTG may protect cardiomyocytes from ischemic death [10]. tTG expression in fibroblasts promotes cell adhesion [11], regulates fibroblast migration, stimulates fibronectin synthesis and has been implicated in organization of the fibroblast-...
However, SrR can cause a number of adverse reactions, including skin damage, ischemic heart disease, peripheral vascular disease, and cerebrovascular disease [159]. This is a major reason why SrR is not widely used in the treatment of osteoporosis [160]. Potential novel therapeutic targets for ...
The recognition of ischemic toxicity and the effort to overcome the toxic effect would help develop alternative approaches in the treatment of ischemic heart disease.doi:10.1007/s12012-012-9174-yWeihong HeY. James KangSpringer NatureCardiovascular Toxicology...