Here, we designed a stem cell-containing patch (stem cell "Janus" patch; SCJP) to acclimatize stem cells in the osteogenic and odontogenic microenvironment for periodontal regeneration. The SCJP promoted periodontal regeneration within its functional layer, while its barrier layer blocked gingival ...
The gel layer may include cells such as, for example, stem cells; the intermediate layer may be biodegradable porous mesh and the reinforcement layer may be polytetrafluoroethylene. Included are methods for making patches according to the invention and for tissue engineering using patches of the ...
I don't know if this is for you but... Just imagine being able to re-activate all the stem cells in your body. How would you feel if all of your aches and pains were a thing of the past and your body was able to turn back the clock and repair rejuvenate rebuild anything that’...
A treatment in development since 2013, the California Project to Cure Blindness—Retinal Pigment Epithelium 1 (CPCB-RPE1) patch consists of a monolayer of human stem cell-derived RPE cells cultured on an ultrathin membrane of biologically inert parylene. The goal for this patch is to replace de...
To achieve this goal, a bioengineered cardiac patch (the MSC patch) composed of a sliced porous biological scaffold inserted with multilayered mesenchymal stem cells (MSCs) was developed for myocardial repair in a syngeneic rat model. After culture, sliced layers of the scaffold were stuck ...
The digital model is made into a physical structure by 3D printing with proteins native to the heart and further integrating cardiac cell types derived from stem cells. Only with 3D printing of this type can researchers achieve one micron resolution needed to mimic structures of native heart tissu...
The digital model is made into a physical structure by 3D printing with proteins native to the heart and further integrating cardiac cell types derived from stem cells. Only with 3D printing of this type can researchers achieve one micron resolution needed to mimic structures of native heart tissu...
Despite increased use of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) for drug development and disease modeling studies, methods to generate large, functional heart tissues for human therapy are lacking. Here we present a “Cardiopatch” platform for 3D culture and maturation...
et al. Dermal adipocyte lipolysis and myofibroblast conversion are required for efficient skin repair. Cell Stem Cell 26, 880–895.e6 (2020). Article CAS PubMed PubMed Central Google Scholar Plikus, M. V. et al. Regeneration of fat cells from myofibroblasts during wound healing. Science ...
Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium Endocrine cells of the pancreas and the gastrointestinal tract derive from multipotent endodermal stem cells. We have shown previously that the basic helix... Jenny,M. - 《Embo ...