doi:10.2217/17460875.3.1.23Anthony S WierzbickiConsultant Chemical Pathologist St Thomas HospitalFuture Medicine LtdFuture LipidolWierzbicki T (2008) Detection of small, dense LDL-cholesterol: is it necessary to determine particle size? Future Lipidol 3:23–25
LDL cholesterol levels and LDL particle number are often concordant (i.e. when one is high, the other is high, and vice versa), and this is probably why there is an association between LDL cholesterol and heart disease in observational studies. The elevated LDL cholesterol was more of a pr...
LDL-C, and LDL-P. Additional values might includevery low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), LDL-C and/or HDL cholesterol, particle, and size.
One such intermediate marker is lipoprotein particle size. Although LDL-cholesterol concentration, not the particle size, remains the primary target of therapy for the prevention of coronary heart disease (CHD),5 increasing research has been devoted to the study of the heterogeneity of LDL particles...
LDL size fat distribution gender HDL HDL2 cholesterol Whereas many studies have examined the lipid and lipoprotein responses to dietary fat and cholesterol in humans and have noted marked interindividual variability (1, 2, 3, 4, 5, 6), there has been less definition of the attributes of indivi...
Lipids contain a high level of unsaturated fatty acids such as palmitic, oleic, linoleic, and linolenic acids and tocotrienols and squalene, with an important role in lowering LDL-cholesterol in the blood8,9. Due to more stability to oxidation than sunflower oil10, the amaranth seeds oil has...
Very-low-density lipoprotein (VLDL) triglycerides and LDL-cholesterol were increased in patients compared with controls (0.89 ± 0.79 mmol/L and 0.54 ± 0.35 mmol/L, p < 0.05, and 4.08 ± 0.85 mmol/L and 3.60 ± 0.92 mmol/L, p < 0.05, respectively) whereas high-density lipoprotein (...
12 were analyzed for LDL particle size distribution and cholesterol content using nuclear magnetic resonance (NMR) spectroscopy. Results: A total of 85 subjects [mean ± SD age: 54.0 ± 12.8 y; BMI: 28.7 ± 3.6 kg/m2] completed the study. Overall, regular-fat cheese did not impact ...
Regular-fat cheese does not seem to increase low density lipoprotein cholesterol (LDL-C) concentrations compared to reduced-fat cheese. However, plasma LDL-C concentrations do not reflect levels and size of LDL particles, which might be a better predictor of cardiovascular risk. Methods The aim ...
To identify the TyG index cutoff value for the predominance of sdLDL particles, receiver operating characteristic curves were plotted. Results Mean LDL particle size correlated more strongly with the TyG index than did very low-density lipoprotein, low-density lipoprotein cholesterol, and high-...