Lumsden J, Sulliman Ch, Dally J, West A, Fenwick PBC, Fenton GW (1994): Petechial haemorrhage following apartial seizure with secondary generalization: atypical presentation an differential diagnosis, Seizure 3: 73-75Lumsden J, Sulliman C, Dally J, West A, Fenwick PB, Fenton GW. Petechial ...
As far as semiology of seizure is concerned, partial seizure with secondary generalization were the most common seizure type found in late-onset epilepsy in elderly followed by simple partial seizure, which was similar to previous study done by Sundaram. A comparative study between early-onset and...
One infant, microcephalic at birth, developed at age 4 months clusters of nearly continuous multifocal seizures with secondary generalization, refractory to antiepileptic drugs. By age 4.5 years she was seizure-free but remains without any cognitive or motor function. Patient 2, born with a normal...
In contrast, a complex partial seizure involves an alteration in consciousness, the patient being unable to interact with and respond to the environment or to recall ongoing events. From: The Comprehensive Evaluation and Treatment of Epilepsy, 1997 ...
In addition, median changes in complex partial plus secondary generalized seizure frequency were also greater with perampanel than placebo (perampanel 4 mg, −31.2%; 8 mg, −35.6%; 12 mg, −28.6%; placebo, −13.9%). Perampanel was generally well tolerated. The most frequent treatment-...
Recently, perampanel, a first-in-class AED was licensed as an adjunct for the management of refractory partial onset seizures with or without secondary generalization in patients 12years and older. This review highlights the current management of partial epilepsy and analyses the published clinical ...
Median total seizure frequency per week was the primary efficacy variable. A total of 280 subjects, most of whom had refractory partial seizures with or without secondary generalization, were evaluated. Most were receiving either one (34.6%) or two (53.2%) concomitant antiepileptic drugs (AEDs) ...
All patients had partial seizures with or without secondary generalization. Compared with baseline, 11 patients (34.4%) had a greater than 50% decrease in seizure frequency, and 4 (12.5%) had a 25% to 50% decrease in seizure frequency. Of the seven children who received the medication for ...
Retigabine for the Adjunctive Treatment of Adults with Partial-Onset Seizures in Epilepsy with and without Secondary Generalization The National Institute for Health and Clinical Excellence (NICE) invited the manufacturer of retigabine (GlaxoSmithKline) to submit evidence for the clinic... D Craig,S Ric...
The initial manifestation was behavioral arrest with staring (69%) and apnea with cyanosis or pallor (37.5%). These symptoms were followed by deviation of eyes or head or both (56%), mild clonic movements (31%), or increased limb tone (35%). Secondary generalization was noticed in 37.5%...