PNH是一种由后天基因突变造成并导致红细胞破裂(医学上称“溶血”)的血液疾病。一般来说,正常红细胞膜上有几种保护性蛋白,可使红细胞免受机体的补体系统(先天免疫系统的一部分)误伤。然而,PNH患者造血干细胞的PIG-A基因发生了突变,突变后血细胞膜表面的锚连蛋白缺失,血细胞失去这些蛋白的保护,对补体高度敏感,进而...
沪江词库精选paroxysmal nocturnal hemoglobinuria是什么意思、英语单词推荐 阵发性睡眠性血红蛋白尿,阵发性夜间血红蛋白尿 相似短语 nocturnal paroxysmal hemoglobinuria夜间阵发性血红蛋白尿症 paroxysmal nocturnal hemoglobinuria阵发性睡眠性血红蛋白尿,阵发性夜间血红蛋白尿 ...
nocturnal paroxysmal hemoglobinuria夜间阵发性血红蛋白尿症 paroxysmal nocturnal hemoglobinuria阵发性睡眠性血红蛋白尿,阵发性夜间血红蛋白尿 nocturnal hemoglobinuria夜间血红蛋白尿 paroxysmal hemoglobinuria阵发性血红蛋白尿症 paroxysmal cold hemoglobinuria阵发性寒冷性血红蛋白尿症 ...
Related to paroxysmal nocturnal hemoglobinuria:Paroxysmal cold hemoglobinuria he·mo·glo·bi·nu·ri·a (hē′mə-glō′bə-no͝o′ē-ə, -nyo͝or′-) n. The presence of hemoglobin in the urine. he′mo·glo′bi·nu′ricadj. ...
LIGHTLY more than 200 cases of paroxysmal nocturnal hemoglobinuria (PNH) have been reported; yet numerous articles have appeared concerning the pathogenesis of this disease. Although the basic abnormality in PNH resides in the red blood cells, hemolysis in PNH depends on a complex hemolytic system ...
“paroxysmal nocturnal hemoglobinuria"在免费英文——中文词典中的翻译 : 陣發性睡眠性血紅蛋白尿.查看更多翻译和示例。
概述 阵发性睡眠性血红蛋白尿(paroxysmal nocturnal hemoglobinuria,PNH)系后天获得性的红细胞膜缺陷引起的对补体激活异常敏感的慢性血管内溶血,常睡眠时加重,可伴间歇性血红蛋白尿和全血细胞减少症或反复血栓形成。 病因和发病机制 PNH 是由于红细胞
Paroxysmal nocturnal hemoglobinuria. 来自 NCBI 喜欢 0 阅读量: 59 作者: CJ Parker 摘要: The aim is to report on recent observations related to the natural history of paroxysmal nocturnal hemoglobinuria (PNH) and to review new therapeutic strategies for controlling the hemolysis of PNH.This review ...
Paroxysmal nocturnal hemoglobinuria in myelofibrosis. Ten consecutive patients with myelofibrosis were examined for the following signs of PNH: Ham's test, the sucrose hemolysis test, low red cell acetylcholinesterase (ACHE) activity and intravascular hemolysis. Two of the patients displaye... NE Hansen...
Natural history of paroxysmal nocturnal hemoglobinuria The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria. Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes... ...