A “brittle response” to levodopa has recently been described in women to define the presence of highly disabling dyskinesias after taking small doses of levodopa (e.g., 100 mg or less per dose). Dyskinesia is strongly correlated with levodopa bioavailability, and women achieve significantly hig...
Parkinson, teléfono móvil y manos de un anciano que escribe en línea para buscar una afección médica YuriArcursPeopleimages Manos, persona mayor y escritura de cartas con bolígrafo para comunicación, franqueo y enfermedad de Parkinson YuriArcursPeopleimages Mujer escribiendo en una computadora...
Modestino EJ, Amenechi C, Reinhofer A, O'Toole P (2017) Side-of-onset of Parkinson’s disease in relation to neuropsychological measures. Brain Behav 19:7(1) Google Scholar Moessnang C, Frank G, Bogdahn U, Winkler J, Greenlee MW, Klucken J (2011) Altered activation patterns within...
En general, la mayoría de los trabajos publicados demuestran que el fenómeno de hipersensibilidad por denervación, o «up-regulation», afecta preferentemente a los receptores dopaminérgicos estriatales D230, 33, como se observa en los resultados obtenidos en este estudio (Figura 4, ...
Krull M, Pistor S, Voss N, Kel A, Reuter I, Kronenberg D, Michael H, Schwarzer K, Potapov A, Choi C, Kel-Margoulis O, Wingender E: TRANSPATH: an information resource for storing and visualizing signaling pathways and their pathological aberrations. Nucleic Acids Res. 2006, 34 (Database...
(E) on PD, which is the outcome of interest (O). An association between the smoking-risk-increasing SNP (S) and elevated risk of PD is consistent with a causal relationship betweenEandOif three assumptions are met: (1) The SNP (S) must be strongly associated with smoking (E); (2)...
Un metanálisis del estudio LARGO parece indicar un comportamiento mejor de la rasagilina que la entacapona en algunos parámetros (marcha y estabilidad postural) de la EP avanzada25. Inhibidores de la catecol-O-metiltransferasa Los inhibidores de la catecol-O-metiltransferasa (COMT) ...
Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O’Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K. ...
Kohler O, Krogh J, Mors O, Benros ME (2015) Inflammation in depression and the potential for anti-inflammatory treatment. Curr Neuropharmacol 7:732–742 Google Scholar Kokovay E, Cunningham LA (2005) Bone marrow-derived microglia contribute to the neuroinflammatory response and express iNOS in ...
Maria Claudia Russillo , Valentina Andreozzi , Roberto Erro , Marina Picillo , Marianna Amboni , Sofia Cuoco , Paolo Barone and Maria Teresa Pellecchia * Center for Neurodegenerative Diseases (CEMAND), Department of Medicine, Surgery and Odontology “Scuola Medica Salernitana”, University of Salern...