For high-risk couples reluctant to undergo an invasive procedure, PBH-NIPT is a more attractive option, requiring only a simple blood draw from the pregnant woman. For most conditions, including the deduction of carrier and normal individuals using NIPT, no further confirmation is needed. For ...
Pregnant KIR2DL1-expressing females from the KIR × C*05 mating did not show evidence of hypertension throughout the course of gestation and post-partum (Supplementary Fig.2a) or of proteinuria (Supplementary Fig.2b), both hallmarks of pre-eclampsia18. We also did not observe any change ...
while the paternal genome from sperm experiences protamine-to-histone exchange. The genomes remain separated as male and female pronuclei before being reunified during the M phase in late zygotes5,6. Although they reside in the same cytoplasm, the ...
pregnant women have enrolled. The results are expected to showcase the importance of biomonitoring for understanding individual risks, and to identify a number of regions where DNA methylation status is altered in the pesticides-exposed population, paving the way for an integrated biomonitoring system ...