The presence of immune cells in the central nervous system has long been the subject of research to find out their role. For a long time it was believed that the CNS was a privileged area from an immunological point of view, due to the presence of the blood-brain barrier (BBB), as ...
The presence of immune cells in the central nervous system has long been the subject of research to find out their role. For a long time it was believed that the CNS was a privileged area from an immunological point of view, due to the presence of the blood-brain barrier (BBB), as ci...
After ischemia, increased βAPP immunolabeling emerged in several brain regions. In the hippocampus, granular deposits appeared in the damaged CA1 area by 2 weeks, and by 4–10 weeks the remnants of necrotic CA1 neurons were also immunolabeled. In striatum and thalamus, regions with necrotic ...
The skull is a hard framework of bone. Tumors in the brain are dangerous because they press on areas of the brain as they grow. The skull is not able to expand to accommodate the presence of a tumor. When the tumor grows, it presses on the brain. Depending on which area of the brai...
Within each rat strain, the microvascular bed properties such as vessel profile frequency (density) varied considerably among the 21 brain areas. In opposition to the hypothesis, mean luminal diameter as well as profile frequency, surface area, and luminal volume of the microvascular beds per unit...
The model was able to predict the pattern of blood–brain barrier damage. We found strong correlation between the area of fibrinogen extravasation and the brain area where axial strain in vessels exceeds 0.14. Our results showed that adjacent vessels can sustain profoundly different axial stresses ...
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2021, Stroke Modified DWI-FLAIR mismatch guided thrombolysis in unknown onset stroke 2019, Journal of Thrombosis and Thrombolysis Focal T2 and FLAIR hyperintensities within the infarcted area: A suitable marker for patient selection for treatment? 2017, PLoS ONE View all citing articles on ScopusView...
[81]. Cell densities were determined by manual counting of cells using the ImageJ cell counter plugin and division through the area considered and given as cells/mm2. Graph PadPrism 6.0 was employed for data plotting. For spatial analysis, manually labeled cell coordinates were used. Kernel ...
In some embodiments, a microdialysis probe provides mass transport in and out of the probe as a function of a concentration gradient across a membrane. Accordingly, the probe can be used to deliver and/or recover compounds from, for example, an extracellular fluid in the local area of implanta...