Thus, after the sequencing of the genome of one of these worms, GPCR identification and annotation is often a priority. Here, we describe a computational pipeline for the identification of orthologous GPCRs in a set of over 50 newly sequenced genomes from parasitic worms.Nicolas Wheeler...
GPCR identification in parasitic worm genome assemblies. Protoc. Exch. https://doi.org/10.1038/protex.2018.061 (2018). Jones, A. K., Davis, P., Hodgkin, J. & Sattelle, D. B. The nicotinic acetylcholine receptor gene family of the nematode Caenorhabditis elegans: an update on nomenclature....
Trichuriasis is caused by infection ofTrichuris trichuira, also known as the human whipworm, and a member of the Trichuridae family. This worm is found worldwide, notably in Asia, Africa and Latin America [164,165] (see Additional file1: Figure S2).T. trichuirahas infected approximately ...
26 The lower helminth prevalence could be due to a deworming program against helminths particularly soil-transmitted helminths and schistosomiasis in Ethiopia.27 Furthermore, because low temperatures are not conducive to helminth infection, the climatic conditions of our study area ...
In 2002,P. falciparumbecame the first parasitic protist to have its entire genome sequenced. The filarial wormB. malayiin 2007 represented the first human-infective multicellular organism so studied. Subsequently, the genomes of a number of parasites have become the subject of intense sequencing. ...
WormBase ParaSite - a comprehensive resource for helminth genomics. Mol Biochem Parasitol. 2017;215:2–10. 19. O'Leary NA, Wright MW, Brister JR, Ciufo S, Haddad D, McVeigh R, Rajput B, Robbertse B, Smith-White B, Ako-Adjei D, Astashyn A, Badretdin A, Bao Y, Blinkova O, ...
This is relevant because in recent years there appears to be an increase in incidences of heart worm (Angiostrongylus vasorum) in canids (dogs and foxes) (Lange et al., 2018). The large numbers of A. vulgaris in gardens and agricultural habitats could be possible intermediate hosts for ...
(Fig.1a). Due to absence ofH. bacteriophorahits in the blastx results, we performed a standalone blastx ofH. indicatranscripts againstH. bacteriophoraprotein dataset (PRJNA13977) downloaded from the wormbase (http://parasite.wormbase.org/ftp.html). The blastx resulted in 2,745 protein ...
Identification of viruses inB. malayiandO. volvulus To further characterize these viruses, we focused on those withinB. malayiandO. volvulus. After assembling transcriptome sequences, we identified seven RNA virus genome sequences, one inB. malayiand six inO. volvulus, with four sequences in the...
Identification and annotation Genomic repeats specific to L. cuprina were modelled using the programme RepeatModeler (http://www.repeatmasker.org/RepeatModeler.html) by merging repeat predictions using RECON (http://selab.janelia.org/recon.html) and RepeatScout (http://bix.ucsd.edu/repeatscout/). ...