Ketorolac tromethamine(Toradol) is safe in single IM doses of 30 to 60 mg and provides excellent 6 to 8 hour analgesia without any sedation. IV Toradol has an extremely short effect, and thus is never useful for significantpostoperative painrelief (as per label warning). Toradol also may be...
Maternal ConsiderationsThere are no adequate reports or well-controlled studies ofbutalbitalin pregnant women. Side effectsinclude thrombocytopenia, Stevens-Johnson syndrome, drowsiness, sedation, constipation, dyspnea, N/V, SOB, and abdominal pain. ...
▪ Breastfeeding Safety There is no published experience in nursing women. It is unknown whether butalbital enters human breast milk. Other barbiturates enter human breast milk, but the kinetics are poorly described. ▪ Drug Interactions No specific interaction studies identified. See phenobarbital...
Moreover, complex investigational and regulatory considerations and the alleged lack of space on the market may discourage the development of new NSAID-based FDCs. 5. Conclusions The combination of NSAIDs with paracetamol or metamizole is a well-established practice in the clinical setting. Despite ...