We report on the paracetamol levels and safety profiles obtained in thirteen babies of <28 weeks GA, using an extended dosage regimen2 over five days with maximum daily dose of 60mg/kg/day; twice that recommended by the BNFC for analgesia in infants <32 weeks gestation.Method Babies <28 ...
BNFc11 Oral Loading dose 20 mg/kg Maintenance 10–15 mg/kg/dose q6–8 h in ≥32 wk q8–12h in <32 wk PMA ≥32 wk PMA, max 60 mg/kg/d <32 wk PMA, max 30 mg/kg/d Rectal Loading dose 30 mg/kg in ≥32 wk Maintenance 20 mg/kg in <32 wk 20 mg/kg q8h (max 60 mg...
https://bnfc.nice.org.uk 5. Harriet Lane Service (Johns Hopkins Hospital). The Harriet Lane Handbook: A Manual for Pediatric House Officers. 21st ed. Hughes HK, Kahl LK, eds. Elsevier; 2018. 6. de Martino M, Chiarugi A, Boner A, Montini G, De’ ...