and pref. Cl ions. (I) is an intermediate. It may be converted to its amide which is itself an intermediate for the prepn. of the known beta-adrenergic blocking agent p-2-hydroxy-3-isopropyl aminopropoxy) phenyl acetamide (atenolol)....
英文别名para-Phenacetin | Acetamide, N-(4-ethoxyphenyl)- | Achrocidin | Coriforte | Seranex | HSDB 3152 | para-Acetophenetidine | Robaxisal-ph | Thephorin A-C | CCRIS 496 | N-para-Ethoxyphenylacetamide | Paratodol | Xaril | Emprazil-C | Melaforte | Treupel | Acet ...
For example, p-hydroxyaniline is employed in the manufacture of analgesics and antipyretics. Other para substituted phenylamines, such as p-chloroaniline, are useful in the manufacture of dyes, medicinals, and resins. The syntheses of para substituted phenylamines vary depending upon the para ...
We started by treatingN-phenoxyacetamide (1a) with 1.0 equiv. ofN-phenylselanylphthalimide (C1); we observed thepara-aminated phenol (2a, acetaminophen) in 47% yield. To our delight, when catalytic amount ofC1(10 mol%) was used,2acan be obtained in 38% yield (Supplementary Table1, ...
optionally with the addition of decolourizing carbon or bleaching earth. They have generally relatively little self-colour and are usually of low solubility in water. In organic solvents such as chlorobenzene, ortho-dichlorobenzene, dimethyl formamide, acetamide and 2-ethoxyethanol they dissolve with in...
hydroxybenzhydrazide [4A3HBH] or 3-amino-4-hydroxybenzhydrazide [3A4HBH] with an equimolar amount of either ter-ephthaloyl chloride [TCl], isophthaloyl chloride [ICl] or mixtures of various molar ratios of TCl and ICl in anhydrous N,N-dime-thylacetamide [DMAc] as a solvent at -10鈩 ...
Additionally, 17 metabolites [an alcohol: Z-2-dodecen-1-ol; an alkyl halide: 1-bromocyclohexane; an amide: N,N'-thylenebis(N-nitroacetamide); an anhydride: trans-(2-octenyl)succinic anhydride; three corbocyclic acids: butanedioic acid, capric acid, 4-hydroxy benzoic acid; a coumarin ...
Accordingly, the compound cyano-hydroxy-methoxybenzylidene amino-phenyl-pyrrolyl-benzoic acid may be promising as an anticancer agent with an IC50 value 4-fold greater than vandetanib 2 [90]. The IC50 of compound N’-(3-chlorobenzoyl)-2-(2,4-dihydroxopyrimidine-5-sulfonamido) benzoyl hydrazide...