In hydatidiform moles, 尾-hCG levels are very high demonstrating an intense trophoblastic activity, whereas PAPP-A levels remain in the normal range. With spontaneous abortions, 尾-hCG levels decline to very low values whereas PAPP-A continues to increase. These observations furnish indirect evidence...
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The Fund seeks long-term capital growth. Under normal circumstances, the Fund will invest at least 80% of its net assets in common stocks of small capitalization and mid-capitalization companies. There is no minimum percentage of assets that must be invested in either small or mid-cap issuers...
5a–c, and Supplementary Data 2), suggesting that the basic mechanism of IGFBP5 cleavage is similar for both PAPP-A2 and PAPP-A. The A799V patient mutation occurs in a region sensitive to mutation with a long-range connection to the active site The PAPP-A2 A799V (also known as A1033V...
As a table of 5 girls we all ordered the ‘sexy pasta’ initially it arrived and it was cold. I informed the waitress it was cold which was not taken well. We got told the pasta had been in the oven for 10 minutes which was normal. They...
Originally discovered in the circulation of pregnant women as a protein secreted by placental trophoblasts, the metalloprotease pregnancy-associated plasma protein A (PAPP-A) is also widely expressed by many other tissues. It cleaves insulin-like growth factor-binding proteins (IGFBPs) to increase th...
Qualitative variables were presented as frequency distri- bution while Normal quantitative data were presented by mean (standard deviation (SD)) and median (inter- quartile range (IQR)) was used to present non-normal data. The two groups were compared using an indepen- dent t-test or Mann-...
(n=26) the median PP13 concentration was 35.8 pg/mL (range: 17.8–85.5 pg/mL) and in PE pregnancies (n=10) with birth prior to week 34, the median PP13 concentration was 30.6 pg/mL (13.1–50.1 pg/mL), compared to controls with a median of 54.8 pg/mL (range: 15.4–142.6 pg/...
Mean PAPP-A levels in controls were 10.68 ± 1.04 ng/ml. In UA cases PAPP-A levels were elevated when the troponin I and CK-MB levels were within the normal range. No correlation was observed between PAPP-A with markers of myocardial necrosis. PAPP-A can serve as a useful ...
In 38% and 71% of cases of trisomy 13 maternal serum free 尾-hCG and PAPP-A was below the 5th centile of the appropriate normal range for gestation and in 62% of cases the nuchal translucency was above the 95th centile. When combined together in a multivariate algorithm with materna...