Debbie L.Hay, ...Paul W.R.Harris, inTrends in Pharmacological Sciences, 2022 STRUCTURE:Atogepant(MK-8031/AGN-241689) is a heavily polycyclic molecule, containing four chiral centers, three aromatic and three aliphatic rings. An intriguing feature is the 2-azaspiro [4.4]nonan-1-one (spiroaz...
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