关键词: 吉西他滨; 培美曲塞; 人胰腺癌细胞; 细胞增殖; 细胞周期中 图分类号:R734.2% % % % % % % % 文献标识码:A% % % % % % % % 文章编号:1673-4254(2010)01-0149-04Effects of gemcitabine and pemetrexed on the proliferation of pancreatic cancer cell linesBXPC-3 and PANC-1 in vitro...
lower than those in the normal control group,while the expression levels of P53and P21showed an upward trend.Conclusion Tau can inhibit the proliferation and migration activity of BxPC-3and PANC-1pancreatic cancer cells,and promote cell apoptosis,possibly by affecting related apoptosis genes and ...
Cell counting kit-8 (CCK-8), cell scratch assay and Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) method were used to observe the effect of Tau on the proliferation, migration and apoptosis of BxPC-3 and PANC-1 cells. Quantitative real-time polymerase chain ...
2.1 正常情况下人胰腺癌BXPC-3及PANC-1细胞生长情况 2株细胞生长呈无限繁殖,在第2天进入对数生长期(图1)。 图1 BXPC-3及PANC-1细胞的生长曲线Fig.1 Proliferation curve of BXPC-3 and PANC-1 cells 2.2 吉西他滨与培美曲塞泰对BXPC-3及PANC-1细胞增殖的影响 吉西他滨(10-7-10mg/ml)与培美曲塞(10-...
仙鹤草水提液对胰腺癌细胞BXPC-3和PANC-1增殖的抑制作用研究 蔡田恬, 赵敏, 王建平, 浙江省中医院, 杭州 310006 详细信息 Inhibitory Effects of Agrimoniae Herba Extracting Solution on Pancreatic Cancer Cell BXPC-3 and PANC-1 Proliferation CAI Tiantian, ZHAO Min, WANG Jianping, Zhejiang Provincial...
BXPC-3细胞周期结果显示:与对照组相比,吉西他滨与培美曲塞分别将细胞周期阻断在G1期和S期(P〈0.05) 同时给药G2期比例减少(P〈0.05) 先用吉西他滨后用培美曲塞将细胞周期阻断在G1期(P〈0.05) 先用培美曲塞后用吉西他滨将细胞周期阻断在S期(P〈0.05).结论吉西他滨与培美曲塞均能抑制人胰腺癌细胞BXPC-3...
·m L^-1仙鹤草水提液对胰腺癌细胞BXPC-3周期分布的影响;Annexin V-FITC/PI双染法检测1,2,4,8 mg·m L^-1仙鹤草水提液对BXPC-3细胞凋亡的影响.结果仙鹤草水提液可显著抑制BXPC-3和PANC^-1细胞的增殖,并呈时间和浓度依赖性;仙鹤草水提液可显著增加BXPC-3细胞停滞在G1期的百分率,促进BXPC-3细胞的早期...
各位大神，本人落座福建福州，向各位求助一株人胰腺癌Panc-1细胞或者原位胰腺癌Bxpc-3细胞，还请各位虫...
Gemcitabine作用于BxPC-3, PANC-1, 和MIA PaCa-2细胞,诱导NF-κB活性,作用于BxPC-3 和PANC-1细胞,降低NF-κB抑制剂 IκBα水平。低剂量Gemcitabine处理BxPC-3细胞48小时提高NF-κB 结合,这种作用存在剂量依赖性。相反, 更高剂量Gemcitabine处理BxPC-3细胞48小时,降低 NF-κB DNA 结合,而更高剂量Gemcitabine处理...
andVandanaPrajapatiandRajeshAgarwalandRanaSDOSCancer LettersIn vitro and in vivo anticancer efficacy of silibinin against human pancreatic cancer BxPC-3 and PANC-1 cells[J] . Dhanya Nambiar,Vandana Prajapati,Rajesh Agarwal,Rana P. Singh.Cancer Letters . 2012...