AEB071是治愈自身免疫病的一种有效治疗策略。根据银屑病面积严重程度指数(PASI)评分,AEB071(300 mg,一天两次,两周)处理后,相比于基线,银屑病的临床严重程度减少高达69%。[2] 参考文献 [1] Skvara H1, et al. The PKC inhibitor AEB071 may be a therapeutic option for psoriasis. J Clin Invest. 2008 Se...
Here we describe the potential synergistic behavior of the therapeutic combination of tamoxifen (TMX), a known inhibitor of PKC, and TMZ in GBM. MethodsWe used two GBM cell lines incubated in absence and presence of TMX and/or TMZ and measured cell viability, proliferation, apoptosis, cell ...
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Here we describe the potential synergistic behavior of the therapeutic combination of tamoxifen (TMX), a known inhibitor of PKC, and TMZ in GBM. Methods We used two GBM cell lines incubated in absence and presence of TMX and/or TMZ and measured cell viability, proliferation, apoptosis, cell ...