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10-day decitabine with venetoclax for newly diagnosed intensive chemotherapy ineligible, and relapsed or refractory acute myeloid leukaemia: a single-centre, phase 2 trial Lancet Haematol., 7 (2020), pp. e724-e736 View PDFView articleGoogle Scholar 7 A.E. Perl The role of targeted therapy in...
Importantly, associations detected in this manner also represent direct observations from actual human tumours; a distinct advantage compared with data from cell culture systems. Still, the principle has not been systematically explored and evaluated in comprehensive human tumour materials. Here we make ...
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landscape received: 06 July 2016 accepted: 25 November 2016 Published: 21 December 2016 Matias M. Falco1, Marta Bleda2, José Carbonell-Caballero1 & Joaquín Dopazo1,3,4 Dysregulation of the normal gene expression program is the cause of a broad range of diseases, including cancer...
View PDFView articleView in ScopusGoogle Scholar E3 N.Q. Phan, C. Blome, F. Fritz, J. Gerss, A. Reich, T. Ebata, et al. Assessment of pruritus intensity: prospective study on validity and reliability of the visual analogue scale, numerical rating scale and verbal rating scale in 471 ...
(CODON_POS). Partitioned analyses assigned a unique instance of the substitution model to each data subset, with joint branch length optimization. Analyses of theBCSL_114taxon set consisted of an adaptive best tree search [49] and an adaptive bootstopping procedure that used theautoMRERAxML boot...
David A Wheeler#154,155, Guanming Wu215, Jun Yu216, Jing Zhang115, Xuanping Zhang145,217, Yan Zhang115,218,219, Zhongming Zhao220, Lihua Zou221 and Christian von Mering120,126 PCAWG Transcriptome Working Group Samir...
Non-alcoholic fatty liver disease is a growing health burden with limited treatment options worldwide. Herein we report a randomized, double-blind, placebo-controlled, multiple-dose trial of a first-in-class pan-phosphodiesterase inhibitor ZSP1601 in 36 NAFLD patients (NCT04140123). There were thre...
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