PAM250 Matrix for 20 Amino AcidsAAPAM
下面,我们举例说明如何得到PAM250矩阵。 对于一条蛋白质序列,我们知道其氨基酸组成,设其组成矩阵(ProteinMatrix)为 其中,表示氨基酸i在肽链中出现的频率,当1%的氨基酸的氨基酸发生突变,这一过程发生第一次时,其氨基酸变化情况实际上符合PAM1矩阵描述的变化, 所以,经过一次1%的氨基酸发生改变的蛋白质的氨基酸组成矩阵: ...
The PAM250 matrix with the amino acids grouped according to the chemistry of the side chainAlexander PertsemlidisJohn W Fondon
PAM250 matrixThe syntheses tableSimilar propertyGraphical theoryIt is well known that there are some similarities among various naturally occurring amino acids. The standard amino acids have been grouped by their general properties and the chemical structures of their side chains. In this paper we ...