Finally, protein S-palmitoylation (radiolabeled) can be detected by fluorography (see Fig. 4A). Incorporation of 3H/14C-labeled palmitic acid into substrate proteins at Cys residues remained a gold standard for
palmitic acidpalmitoylationHigh serum level of palmitic acid(PA) is implicated in pathogenesis of cardiovascular diseases. PA serves as the substrate for protein palmitoylation. However, it is still unknown whether palmitoylation is involved in PA-induced cardiovascular dysfunction. Here, in...
Palmitic acid structure CAS No. 57-10-3 Chemical Name: Palmitic acid Synonyms N-HEXADECANOIC ACID;HEXADECANOIC ACID;C16;palmitic;Palmic acid;CETYLIC ACID;1-Pentadecanecarboxylic acid;Hydrofol;PALMITINSAEURE;Hexadecylic acid CBNumber: CB9388222 ...
Reprogramming of palmitic acid induced by dephosphorylation of ACOX1 promotes β-catenin palmitoylation to drive colorectal cancer progression Qiang Zhang, Xiaoya Yang, Jinjie Wu, Shubiao Ye, Junli Gong, Wai Ming Cheng, Zhanhao Luo, Jing Yu, Yugeng Liu, Wanyi Zeng, Chen Liu, ...
Reduced S-palmitoylation of ciliary proteins, including ADP ribosylation factor like GTPase 13B, results in the loss of cilia. Restoring palmitic acid availability, either through pharmacological inhibition of stearoyl-CoA desaturase 1 or a palmitic acid-enriched diet, significantly restores endothelial ...
Alkynyl Palmitic Acid can be used to identify and characterize the post translation S-palmitoylation of proteins. The terminal carboxylic acid can react with the primary amine group in the presence of an activator (such as EDC or HATU) to form a stable amide bond.四、结构式：五、相关点击试剂...
二、产品描述---Product Description：Alkynyl Palmitic Acid可用于识别和表征蛋白质的翻译后S-棕榈酰化反应，一般炔丙基通过铜催化的叠氮炔点击化学与含叠氮化合物或生物分子反应，产生稳定的三唑键。Alkynyl Palmitic Acid can be used to identify and characterize post translational S palmitoylation of proteins. ...
Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma 2023, Nature Communications Palmitic Acid, A Critical Metabolite, Aggravates Cellular Senescence Through Reactive Oxygen Species Generation in Kawasaki Disease 2022, Frontiers in Pharmacology ...
We report here that neuritogenesis-promoting ligand-dependent cell surface clustering of CHL1 induces palmitoylation and lipid raft-dependent endocytosis of CHL1. We identify ßII spectrin as a binding partner of CHL1, and we show that partial disruption of the complex between ... More Robust ...
1, lane h), indicating that palmitoylation is likely to be a common feature of hedgehog proteins. The ability to label Shh directly with radioactive palmitic acid in a cell-free system provided a simple screen for the amino acid residues required for modification. The role of Cys-24 is ...