这个基因编码一种可能抑制肿瘤的蛋白质。这种蛋白与乳腺癌2早发蛋白(BRCA2)在核病灶结合并与之共定位,可能允许BRCA2稳定的核内定位和积累。 This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) ...
PALB2 (partner and localizer of BRCA2) 这个基因编码一种可能抑制肿瘤的蛋白质。这种蛋白与乳腺癌2早发蛋白(BRCA2)在核病灶结合并与之共定位,可能允许BRCA2稳定的核内定位和积累。 This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the ...
1)PALB2 genePALB2基因 1.At the same time, we performed a case-control study about the common single nucleotide polymorphisms of PALB2 gene and its correlation with the breast cancer susceptibility of Shanghai female breast cancer to evaluate the role of genetic variants of PALB2 in the et...
这个基因编码一种可能抑制肿瘤的蛋白质。这种蛋白与乳腺癌2早发蛋白(BRCA2)在核病灶结合并与之共定位,可能允许BRCA2稳定的核内定位和积累。 This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) ...
Partner and localiser of BRCA2 (PALB2), also known as FANCN, is a key tumour suppressor gene in maintaining genome integrity. Monoallelic mutations of PALB2 are associated with breast and overian cancers, while bi-allelic mutations cause Fanconi anaemia (FA). In the pres...
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008] [中...
Stewart AK, Bekaii-Saab TS, Jewel Samadder N. Germline Cancer Susceptibility Gene Testing in Unselected Patients With Colorectal Adenocarcinoma: A Multicenter Prospective Study. Clin Gastroenterol Hepatol. 2022 Mar;20(3):e508-e528. doi: 10.1016/j.cgh.2021.04.013. Epub 2021 Apr 20. PMID: 33857...
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. ...
Miao, R.; Blue, K.; Sommerer, K.; Shah, A.; Bottiglieri, S.; del Cueto, A.; Berry, D.K.; Ho, T.T.; Hicks, J.K.; Kim, D.W. PARP Inhibitors in Pancreatic Cancer with Homologous Recombination Repair Gene Mutations: A Single-Institution Experience. Cancers 2024, 16, 3447. htt...
[7] Palmer JR, Polley EC, Hu C, et al: Contribution of germline predisposition gene mutations to breast cancer risk in African American women. J Natl Cancer Inst 112:1213-1221, 2020 责任编辑:肿瘤资讯-饶运双 排版...