Molecular Plant 7(3): 492-501. doi: 10.1093/mp/sst172Da Ines O, Gallego ME, White CI. Recombination-independent mechanisms and pairing of homologous chromosomes during meiosis in plants. Mol Plant. 2014; 7(3): 492-501. doi: 10.1093/mp/sst172 PMID: 24375719...
reduction and recombination: an evolutionary hypothesis of meiosis. Nature 222:1275–1276S M StackW V BrownWITH the development of the concept that meaningful pairing of homologous chromosomes and crossing over occur only during meiotic prophase has come a series of reports of somatic pairing of ...
XY diploid). In particular, by taking advantage of the parent-specific single nucleotide variants (SNVs) in this cell line, we provide a global assessment of different properties of homolog pairing, including how tightly apposed homologous chromosomes are ...
(1) that homologous chromosome pairing is normally mediated by nuclear envelope attachment sites; (2) that crossover site establishment awaits synaptic completion; and (3) that it is the function of the synaptonemal complex to hold homologues in register so that equal crossing over can occur, ...
Pairing and recombination of homologous chromosomes are essential for ensuring reductional segregation in meiosis. However, the mechanisms by which chromosomes recognize their homologous partners are poorly understood. Here, we report that the sme2 gene encodes a meiosis-specific noncoding RNA that mediat...
Partitioning of homologous chromosomes at the first meiotic division requires a coordinated set of activities unique to meiotic prophase I that culminates in the establishment of physical associations between pairs of homologous chromosomes. At the onset of meiosis, two important distinctions from ...
The idea that the activity of a genetic element is affected by interactions with other parts of the genome in the nucleus goes back to a conjecture by Müller, who was impressed by the extent of somatic pairing of homologous chromosomes in Drosophila [1]. This physical pairing, particularly vi...
What about homologous chromosomes? Chromosomes adopt a distinct position in the nucleus based on gene density, expression status, and number of repetitive elements. As such, chromosomes of similar size and gene density are more likely to interact in mouse and human cells [20, 21, 22]. Thus, ...
Recombination is also considered to be dependent on factors that stabilize interactions between homologous chromosomes. In budding yeast Hop2 and Mnd1 act as a complex to promote homologous pairing and recombination in conjunction with Rad51 and Dmc1. Results We have analyzed the function of the ...
During meiosis, homologous chromosomes (homologues) recognize each other and then intimately associate. Studies exploiting species with large chromosomes reveal that chromatin is remodeled at the onset of meiosis before this intimate association. However, little is known about the effect the remodeling has...