Pairing and recombination of homologous chromosomes are essential for ensuring reductional segregation in meiosis. However, the mechanisms by which chromosomes recognize their homologous partners are poorly understood. Here, we report that the sme2 gene encodes a meiosis-specific noncoding RNA that ...
During meiosis, homologous chromosomes pair with each other and undergo... DQ Ding,T Haraguchi,Y Hiraoka - 《Chromosome Research》 被引量: 11发表: 2013年 Chromosomally-retained RNA mediates homologous pairing Meiosis-specific noncoding RNA mediates robust pairing of homologous chromosomes in meiosis....
Partitioning of homologous chromosomes at the first meiotic division requires a coordinated set of activities unique to meiotic prophase I that culminates in the establishment of physical associations between pairs of homologous chromosomes. At the onset of meiosis, two important distinctions from ...
Pairing of homologous chromosomes in meiosis is critical for their segregation to daughter cells. In most eukaryotes, clustering of telomeres precedes and facilitates chromosome pairing. In several species, centromeres also form pairwise associations, known as coupling, before the onset of pairing. We...
Background Pairing of homologous chromosomes at meiosis is an important requirement for recombination and balanced chromosome segregation among the products of meiotic division. Recombination is initiated by double strand breaks (DSBs) made by Spo11 followed by interaction of DSB sites with a homologous...
New analyses reveal that TERRA transcripts arising from the subtelomeric pseudoautosomal (PAR) region of sex chromosomes nucleate pairing of X alleles in mouse ES cells. In mammals, homologous chromosomes rarely pair outside meiosis. One exception is the
Pairing of homologous chromosomes is important for homologous recombination and correct chromosome segregation during meiosis. It has been proposed that te... HY Hiraoka - 《Developmental Cell》 被引量: 333发表: 2004年 The onset of homologous chromosome pairing during Drosophila melanogaster embryogenesis...
segment.3 to.4 the length of an arm is low (.13, ranging from.02 to.29).-We can predict that in an intercross in which both breakpoints in both parental interchanges are far out on the chromosomes, "pairs" will be formed with nonhomologous ends (homologous differential segments paired)...
Pairing describes the side-by-side alignment of homologous chromosomes at a distance. Homologs are paired in nonmeiotic (somatic) cells in a few organisms, such as the fruit fly D. melanogaster, but not in vertebrates. The earliest pairing events in meiosis involve a tendency of homologous chro...
SOME recent claims in connexion with the cytological explanation of meiosis raise very important questions when taken in conjunction with morphological development. This matter is brought to a climax by the recent report in NATOBE of a paper read by Prof. C. L. Huskinsto the Royal Society of...