This article will explain when it is appropriate to use a paired t-test versus an unpaired t-test, as well as the hypothesis and assumptions of each. What is a paired t-test? A paired t-test (also known as a dependent or correlated t-test) is a statistical test that...
The chapter explores the merits of paired versus unpaired experimental designs. General statistical methods such as sample size estimation, determination of practical significance and one-sided testing can be applied to the paired t-test in the same manner that we have already seen for the two-...
C. J. Roberts and W. J. Dupps Jr., "Paired versus unpaired significance testing: how improper statistical analysis altered interpretation of posterior surface changes after LASIK," Journal of Cataract & Refractive Surgery, vol. 40, no. 6, pp. 858-861, 2014....
As you will see from the next example, the analysis of paired samples is done by looking at the difference between the two measurements. As a result, this case uses the same techniques as for the one-sample case, although usually, it is easier to use either the paired t-test data analy...
activity compared to that of pGL4.23 empty plasmid (n = 3 independent biological samples; bars show mean ± s.d.; de_novo_1 NSP = 0.1867, FOXP1_Fl NSP = 0.7006, PBX3_Cl **P = 0.0065, PAX6_Ta NSP = 0.7339 calculated using two-tailed unpaired t-test). ...
For metabolomic data, distributions were examined for normality using the Kolmogorov–Smirnov test. When the distribution was normal, unpaired t-tests was used. Otherwise, the Mann–Whitney U-test was used. The Benjamini–Hochberg method was used to adjust p values for multiple testing with ...
In a subset of seven COVID-19 patient nares samples stored in 95% EtOH, we also detected significantly higher SARS-CoV-2 viral load in RNA extracted from the swab head versus eluent (Fig. 1b; one-tailed paired Student’s t test, p = 0.03). To more quantitatively determine the effects...
On this basis, the high-frequency magnetic-magnetic paired associated stimulation mode formed by combining unpaired peripheral combined central magnetic stimulation and the classic PAS mode may have the advantages of both. As described in the classic rehabilitation treatment technique “forced movement ...
We found a spatial pattern in the relatedness structure between paired males and unpaired males, and this provides context for our findings that relatedness between cuckolds and cuckolders is elevated in this system. We focused here on unpaired males because they commit the vast majority of cuckold...
The unpaired regions are copied from the available strands and the quality score for these regions is the product of the probability of those bases being correct. For the overlapping region, the decision-making process is more complex. If the bases agree, the base is included and the quality ...