After quantile normalization, we removed the probes with detecting p-values > 0.05 in all of the samples. The average of signal (AVG_signal) of each probe was calculated from duplication of expression data. Differentially expressed genes were identified as having a ≥1.25-fold change in ...
We found that target mRNAs that had the most negative correlations coefficients (lower 20th quantile) with the miRNA tended to be more downregulated in the transfection experiment than mRNAs with higher correlation coefficients (upper 20th quantile) (Fig. 2G). Thus, the transfection experiments are...
aUMAP embedding plot of 5992 myeloid cells grouped into 11 clusters.bA dot plot showing marker genes across myeloid clusters from the adjacent UMAP embedding plot (a). The dot size indicates the fraction of expressed cells, and the color represents the normalized expression level.cBar plots showi...