Chemical excitants of pain receptors include exogenous substances, which are foreign to the body, and endogenous substances which occur naturally in the body. Endogenous pain-producing substances include acetylcholine, HCl in gastric juice (at pH<3.0), potassium ions, 5-hydroxytryptamine, and plasma ...
If heat over 40 degrees Celsius is applied to the skin near to where internal pain is felt, it switches on heat receptors located at the site of injury. These heat receptors in turn block the effect of chemical messengers that cause pain to be detected by the body. The team found that ...
④Human brain-imaging studies have implicated(牵涉、暗示) this pain-modulating circuit(环线、回路) in the pain-relieving effect of attention, suggestion, and opioid(阿片类) analgesic(止痛剂) medications. Furthermore, each of the component structures of the pathway contains opioid receptors and is ...
Blockade of N-methyl-D-aspartate receptors by ketamine produces loss of postnatal day 3 monkey frontal cortical neurons in culture. Toxicol. Sci. 91, 192–201 (2006). CAS PubMed Google Scholar Zhou, L. et al. Neonatal exposure to sevoflurane may not cause learning and memory deficits and...
名词distresshurtirritationsufferingpain in the neckpangachesorenessdiscomfort pain 反义词 及物动词joydelightrelievecomfortpleaseease pain 相关词组 pain的反义词 1. a pain in the neck : 讨厌的家伙, 可恶的家伙, 使人厌烦的责任, 使人厌烦的义务;
The role of N-methyl-D-aspartate (NMDA) receptors in pain: a review. There is accumulating evidence to implicate the importance of N-methyl-D-aspartate (NMDA) receptors to the induction and maintenance of central sensitizati... AB Petrenko,T Yamakura,H Baba,... - 《Anesthesia & Analgesia...
It was Dr Lynne Sneddon, at the University of Liverpool, who proved scientifically that fish feel pain and suffer. Her team found 58 receptors located on the faces and heads of trout that responded to harmful stimuli. They resembled those found in other vertebrates, including humans. A ...
Neurosteroidogenesis is required for the physiological response to stress: role of neurosteroid-sensitive GABAA receptors The hypothalamic-pituitary-adrenal (HPA) axis, which mediates the body's response to stress, is largely under GABAergic control. Here we demonstrate that c... S Jhimly,W Seth...
Preliminary data suggest that some of the newer antidepressants, including agents that act on several receptors (eg, norepinephrine and serotonin), may be useful in chronic pain.170-173 However, larger clinical trials on non–tricyclic antidepressants in patients with comorbid depression and pain are...
Sensory pain receptors (also known as nociceptors) are sensory neurons that are attached to thin afferent nerve fibres (located at the skin, muscle, joints, bone, and viscera) and terminate in the dorsal horn of the spine17. Nociceptors help detect signals from potentially damaging stimuli in ...