Hand-foot syndromePaclitaxelHand-foot syndrome (HFS), also known as acral erythema or palmoplantar dysesthesia, is a manifestation of painful erythema and dysesthesia mostly occurring in the palms and soles. Although many chemotherapeutic agents have been shown to cause HFS, it remains an uncommon ...
Significantly more patients in the nab-paclitaxel arm experienced any-grade neutropenia (87.3% vs. 81.5%;P=.007), rash (33.2% vs. 23.1%;P˂.001), hand–foot syndrome (27.7% vs. 17.6%;P˂.001) and peripheral sensory...
The increased rate of grade 3–4 adverse events related to the addition of capecitabine, being hand-foot syndrome (34% versus 0% for AT) and neutropenia (20% versus 12% for AT), generally did not preclude continuation of treatment. Exploratory analyses indicated that 1) patients receiving ...
Hand-foot syndrome ITT: Intention to treat mBC: Metastatic breast cancer OS: Overall survival PD: Progressive disease PFS: Progression-free survival QALM: Quality adjusted life month QoL: Quality of life RECIST: Response evaluation criteria in solid tumors RR: Response rates SAKK: ...
来自 Springer 喜欢 0 阅读量: 13 摘要: The article presents a case study of five stage one to three breast cancer patients who have graded three hand-foot syndrome and other toxicities while they received docetaxel. 展开 年份: 2014 ...
Severe hematological side effects related to epirubicin and paclitaxel were evenly distributed between the treatment arms, mucositis, diarrhea, and Hand-Foot syndrome were significantly more frequent in the TEX arm. Toxicity-adjusted treatment with ET and TEX showed similar efficacy in terms of PFS, ...
The most common grade 3 or worse adverse events were neutropenia (54 [19%] of 284 patients in the bevacizumab plus paclitaxel groupvs5 [2%] of 277 patients in the bevacizumab plus capecitabine group), hand–foot syndrome (1 [<1%]vs43 [16%]), peripheral neuropathy (39 [14%]vs1 [<1%...
The most common adverse events of grade 3 or higher were neutropenia (51 [18%]), peripheral neuropathy (39 [14%]), and leucopenia (20 [7%]) in the paclitaxel group and hand-foot syndrome (44 [16%]), hypertension (16 [6%]), and diarrhoea (15 [5%]) in the capecitabine group. ...
Hand-foot syndromepaclitaxelpyridoxineHand-foot syndrome (HFS) is a relatively frequent adverse reaction to certain anticancer drugs. HFS is a type of dermatitis which has been most commonly described with 5-fluorouracil and capecitabine. However, HFS with paclitaxel is rare and has been reported ...
A 72-year-old woman developed hand-foot syndrome (HFS) while receiving paclitaxel. The woman was diagnosed with infiltrating ductal carcinoma of the right breast, which was stage T1N3M0, oestrogen receptor-positive, progesterone receptor-positive and HER2/neu -negative. After partial mastectomy and...