Dose reductions (by 20 %, per protocol) were more frequent in the 150 mg/m2 qw 3/4 cohort (47 %) than in the other treatment arms (18 % and 20 % in the 100 mg/m2 qw 3/4 and the 300 mg/m2 q3w arms, respectively). More dose delays also occurred in the 150 mg/m2 qw 3/...
On theother hand, the mean cost of VC for one month was approximately 816,000 yen per patient. Although the cost of W-PTX for inpatient did not differ greatly from the cost of VC, the cost of W-PTX for outpatients was significantly lower than that of VC. The findings of this study ...
Advanced breast cancer: use of resources and cost implications. Br J Cancer 1993; 67: 856–60 Article PubMed CAS Google Scholar Eisenhauer EA, ten Bokkel Huinink WW, Swenerton KD, et al. European-Canadian randomized trial of paclitaxel in relapsed ovarian cancer: high dose versus low-dose...
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OBJECTIVE: To study cost-effectiveness of the same drug with different dose for the treatment of the same disease, in order to make a rational drug use pro... Z Sun,Z Yang,J Pei,... - 《Evaluation and Analysis of Drug-use in Hospital of China》 被引量: 0发表: 2005年 The Role of...
The cost per QALY gained by is $8615, and ranges between $3943 and $9416 in sensitivity analyses. These results confirm those of an earlier model using preliminary data and compare favorably with other cost-utility results in this patient group. 展开 ...
To bypass the dedifferentiation step, Lee isolated and cultured CMCs which produced a combined total of 264 mg of paclitaxel per kg of cells and 74% of this was secreted directly into the medium [18, 19]. These cells may provide a cost-effective and environmentally friendly platform for ...
over 30 min, fractionated for 2 days (days 1, 2: 40 mg m−2 per day; total dose 80 mg m−2) with adequate vigorous pre- and post-hydration, mannitol and furosemide diuresis, and electrolyte replacement, 20 mequiv. potassium chloride and 8 mequiv. magnesium sulphate ...
(2 months vs 6 months,P=0.008).Cox regression showed that the PFS of docetaxel had no association with the dose of body surface area per units,age,pathological type,status of estrogen/progesterone receptor,status of Her-2,lymph node metastatic status in patients with paclitaxel-resistant ...
Fig. 5: BIM induced by low-dose paclitaxel binds MCL1 and disrupts the BAK/MCL1 complexes. a Spearman correlation analysis between protein levels (ng/105 cells) of BAK and %BAK/BCLXL + %BAK/MCL1. b After paclitaxel sensitive (OVCAR8, HO8910, A2780) and paclitaxel insensitive cells ...