BACKGROUND: Anthracycline-containing chemotherapy has represented the standard treatment for advanced breast cancer. However, it is sometimes difficult to continue it because of its cumulative cardiac toxicity, and the benefit of adding anthracyclines to the chemotherapy regimen is confined to HER2-...
Paclitaxel and recombinant human granulocyte colony-stimulating factor as initial chemotherapy for metastatic breast cancer. J Clin Oncol 1993 ; 11: 1943–51.Greinix HT, Linkesch W, Seifert M, et al. Paclitaxel-contain- ing high-dose chemotherapy in high-risk breast cancer patients. Acta Oncol...
At 10 Years, DCIS Patients' Risk of Breast Cancer Death Is Very Low Tumor Cells in Marrow May Better Predict Metastases Than Axillary Node Dissection Survey Finds 122 New Anti-HIV Medicines Currently Being Tested Delaying Radiotherapy to Allow Adjuvant Chemotherapy Not Shown to Increase Ipsilateral R...
Weekly adjuvant paclitaxel improves survival after standard chemotherapy in breast cancerdoi:10.1038/ncponc1171NoneNature Clinical Practice OncologyWeekly adjuvant paclitaxel improves survival after standard chemotherapy in breast cancer. Nature Clinical Practice Oncology 5 , 498-498 /...
The response for cytotoxic agents also different according to tumor subtypes. HER2-enriched and basal-like subtypes are more responsive to chemotherapy than the luminal A subtype.3 Chemotherapy for patients with breast cancer is effective in not only reducing recurrence of this disease and improv- ...
Taxanes are among the most widely used chemotherapy agents in the treatment of early-stage and metastatic breast cancer (MBC) [1–4]. Taxanes stabilize microtubules, leading to cell cycle arrest and, ultimately, cell death [5–7]. Guidelines by the National Comprehensive Cancer Network currently...
[4]. Li Q, et al. Low doses of paclitaxel enhance liver metastasis of breast cancer cells in the mouse model. FEBS J. 2016 Jun 16. [5]. Yilmaz E, et al. Sensory neuron subpopulation-specific dysregulation of intracellular calcium in a rat model of chemotherapy-induced peripheral neuropath...
Chemotherapy plays an important role in the management of metastatic breast cancer. The anthracyclines (doxorubicin, epirubicin) and the taxanes (paclitaxel, docetaxel) are considered the most active agents for patients with advanced breast cancer. Traditionally, the anthracyclines have been used in combi...
NM Iyengar,MN Fornier,SM Sugarman,... - 《Other》 被引量: 0发表: 2016年 Paclitaxel and Trastuzumab for Breast Cancer. The complexity of cancer chemotherapy requires pharmacists be familiar with the complicated regimens and highly toxic agents used. This column reviews vari... Lehmann,Thomas,So...
there is evidence of extraglobar extension, or if patients have symptoms or signs of CNS or systemic spread (stages III or IV), both procedures should be performed to accurately stage disease and provide baseline measurements of tumor involvement for monitoring of response to chemotherapy and/or ...