Ratio MRI Magnetic resonance imaging N Number NE Norepinephrine NOMI Non-occlusive mesenteric ischemia PD Peak density PV Portal vein PaO2/FiO2 Ratio of arterial oxygen partial pressure to fractional inspired oxygen ROI Region of interest ROIRef Reference region of interest ROIPV Region...
Nebulized recombinant tissue plasminogen activator (rt-PA) has the potential to facilitate localized thrombolysis in the alveolar compartment and improve oxygenation. In this proof-of-concept safety study, adults with COVID-19-induced respiratory failure and a 2/FiO2 (P/F) ratio requiring invasive ...
lung injury and PaO2/FiO2 <200 mmHg; 6) serum creatinine >176.8 μmol/L (2.0 mg/dl); 7) bilirubin >34.2 μmol/L (2.0 mg/dl); (8) platelets <100,000/μL; and/or 9) blood coagulation disorders (international normalized ratio (INR) >1.5)...
Adjusted regression analysis from symptom day 15 onwards showed a 100mmHg decrease in PaO2/FiO2(primary outcome) for each 37.7pg/ml increase in highest fIL-18 (p<0.03). Per 50pg/ml increase in highest fIL-18, adjusted logistic regression gave an odds-ratio (OR) for crude 60-day mortality...
Time to clinical improvement using 7-point ordinal scale, ventilator/respiratory failure-free days, change in SpO2/FiO2 ratio, and biomarkers of severe COVID-19 were explored. Results: Geometric mean ratio (point estimate [90% confidence interval]) of the relative cha...