p90RSK2, a new MLCK mediates contractility in myosin light chain kinase null smooth muscleMLCKPDK1Pyk2RSK2mylk1p90 ribosomal S6 kinasesmooth muscleIntroduction: Phosphorylation of smooth muscle (SM) myosin regulatory light chain (RLC20) is a critical switch leading to SM contraction. The canonical ...
Pull-down assays showed that luteolin binds JNK1 in an ATP-competitive manner and p90RSK2 in an ATP-independent manner. Luteolin also inhibited UVB-induced wrinkle formation and MMP-13 expression, a rodent interstitial collagenase in mouse skin, in vivo. Taken together, our observations suggest ...
Journal of Translational Medicine (2024) 22:653 https://doi.org/10.1186/s12967-024-05456-5 Journal of Translational Medicine RESEARCH Open Access EGFR mutations induce the suppression of CD8+ T cell and anti‑PD‑1 resistance via ERK1/2‑p90RSK‑TGF‑β axis in non...
As with MCAO animal model, artemether promoted the activation of Erk1/2-P90rsk-CREB signaling pathway. This effect was blocked by the inhibition or knock-down of ERK1/2. The present study provides evidences of the neuroprotective effect of artemether unravelling its potential as a new ...
Pretreatment with U0126 also abrogated the effects of EA at acupoints on pMEK1/2, pERK1/2, pp90RSK, pBad, and NeuN expression, but did not influence BDNF and pRaf-1 expression. Conclusion Overall, our study results indicated that EA at acupoints, initiated 1 d postreperfusion, up...
产品名称:Anti-p90 RSK (Ab-573) Antibody 产品型号: 产品展商:其它品牌 产品文档:无相关文档 简单介绍 Anti-p90 RSK (Ab-573)Antibody Anti-p90 RSK (Ab-573) Antibody的详细介绍 Target Function:Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system...
p90rsk-1在绵羊卵母细胞体外成熟过程中的表达 采用Western blotting检测p90rsk-1在绵羊卵母细胞体外成熟过程中的表达.实验分别在0h,8h,16h,24h检测绵羊卵母细胞p90rsk-1的表达量的变化,并进行统计学分析.结果p90rs... 白瑞霞,曹贵方,赵鹏伟 - 《内蒙古大学学报(自然科学版)》 被引量: 0发表: 2011年 ...
EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2 . Oncogene . 1997. December; 15 ( 4 ):373–83.Douville E, Downward J 1997. EGF induced SOS phosphorylation in PC12 cells involves p90 RSK-2 . Oncogene 15 :373–383. doi:.10.1038/sj.onc.1201214 [ Cross Ref ]...
2001 . ERK2- and p90(Rsk2)-dependent pathways regulate the CCAAT/enhancer-binding protein-beta interaction with serum response factor . J Biol Chem 276 : 38449 – 38456 .Hanlon M, Sturgill TW, Sealy L 2001 ERK2- and p90Rsk2- dependent pathways regulate the CCAAT/enhancer- binding protein...
(1997) EGF induced SOS phosphorylation in PC12 cells involves p90 RSK-2. Oncogene 15, 373-383Douville, E., and Downward, J. (1997). EGF induced Sos phosphorylation in PC12 cells involves P90 RSK-2. Oncogene 15, 373-383.Douville E, Downward J. EGF induced SOS phosphorylation in PC12 ...