The present invention relates to a new p75NTR neurotrophin binding protein (NBP)-Fc fusion protein comprising a p75NTR (NBP) portion and an immunoglobulin portion. In certain embodiments, the p75NTR (NBP)-Fc fusion protein is for use in the treatment of pain and/or a symptom of pain.Simon...
ProNTs截断体与sortilin蛋白相互作用及重组p75NTRFc对Aβ2535PC12细胞毒性作用的影响,ProNTs截断体与sortilin蛋白相互作用及重组p75NTRFc对Aβ2535PC12细胞毒性..
重组人p75NTR169-Fc抗酶裂嵌合体在大肠杆菌中的表达、纯化及活性鉴定
p75 neurotrophin receptor (p75NTR) mediates the inhibitory effects of myelin-associated inhibitors on axonal regeneration after spinal cord injury. Therefore, the p75NTR antagonist, such as recombinant p75NTR protein or its homogenates may block the inhibitory effects of...
p75NTR在谷氨酸诱导海马神经元兴奋毒性损伤中的表达
Fc融合蛋白基因表达毕赤酵母为在酵母细胞中表达出具有生物活性的p75NTR Fc融合蛋白 ,采用PCR方法分别扩增α因子 (α factor)和p75NTR Fc基因 ,经重叠PCR ,获得α factor p75NTR Fc基因 .DNA序列分析该融合基因后 ,插入pAO815载体并构建串联多拷贝表达载体pAO815 3α factor p75NTR Fc .重组质粒电转化酵母GS115...
The present invention relates to a p75ntr-fc neurotropin (nbp) binding protein fusion protein comprising a p75ntr (nbp) moiety and an immunoglobulin moiety. In certain embodiments, the p75ntr (nbp) -fc fusion protein is for use in treating pain and / or a pain symptom.SIMON WESTBROOK...
The present invention relates to a new p75NTR neurotrophin binding protein (NBP)-Fc fusion protein comprising a p75NTR (NBP) portion and an immunoglobulin portion. In certain embodiments, the p75NTR (NBP)-Fc fusion protein is for use in the treatment of pain and/or a symptom of pain.Simon...
p75NTR Fc段PCR扩增神经营养因子受体Objective: To clone, express, and identify the extracellular domain gene of human p75 neurotrophin receptor with IgG-Fc (hp75NTR-Fc) in prokaryotic expression system, and investigate the effect of the recombinant protein on dorsal root ganglia (DRG) neuron ...
Fc融合蛋白基因表达毕赤酵母为在酵母细胞中表达出具有生物活性的p75NTR Fc融合蛋白 ,采用PCR方法分别扩增α因子 (α factor)和p75NTR Fc基因 ,经重叠PCR ,获得α factor p75NTR Fc基因 .DNA序列分析该融合基因后 ,插入pAO815载体并构建串联多拷贝表达载体pAO815 3α factor p75NTR Fc .重组质粒电转化酵母GS115...