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Therefore, we next analyzed the protein-coding potential of GAS6-AS1with four independent mathematical methods, including Coding Potential Assessment Tool [21], Coding Potential Calculator [22], length and guanine-cytosine (LGC) algorithms [23] and ORF finder software from NCBI (Supplementary Figs....
In the human genome, GCAT1 resides on chromosome 11p11.2 as part of an intergenic fragment between the genes CHST1 and SLC35C1. The coding potential calculator18 and coding-potential assessment tool19 confirmed that GCAT1 is a non-coding RNA due to its negligible protein-coding potential (Fi...
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Meanwhile, GSTP1 I/V and V/V genotypes were significantly associated with prostate cancer where the PSA level was more than 10.0 (OR 2.73, 95 % CI 1.319–5.639, p = 0.006). Thus, our data imply that the GSTT1-null genotype may not be a risk factor but a protective factor of ...
S1C). The coding potential calculator (CPC2) [11] and coding-potential assessment tool (CPAT) [12] confirm that ENST00000436340 is a noncoding RNA due to its negligible protein-coding potential (Fig. S1D). Intriguingly, an evolutionary analysis of the ENST00000436340 nucleotide sequence using ...