Innovative therapeutic strategies for esophageal squamous cell carcinoma (ESCC) are urgently required due to the limited effectiveness of standard chemotherapies. C-Terminal Binding Protein 1 (CtBP1) has been implicated in various cancers, including ESCC. However, the precise expression patterns and func...
Analysis of Contributions of the Enzyme-substrate Interactions to Purine Specificity of BarnaseNina Struminskaya
The substrate- active site residues interaction distances are different across the enzymes studied with the enzyme from Bacillus Cereus (1PTG) having better affinity for all substrates. Although electrostatic interactions are most favorable in the Listeria Monocytogenes enzyme (1AOD), we find that ...
Enzyme treatment produced six main peaks which were present in all chromatographs generated from each of the four leaf positions assessed (Figure 3). The arabinoxyloglucan oligosaccharide 4 (identified as peak 4) was found to vary in concentration as a function of leaf position (Figure 3). ...
Related CategoriesEnzyme Inhibitors, Enzyme Inhibitors by Type, Substrate Analogs, 生化试剂, 酶、抑制剂和底物 Less... InChI KeyBFBDFBHROZLGEG-JJCYRVQFSA-K assay≥95% formpowder colorwhite to off-white solubilityH2O: 50 mg/mL storage temp.?20°C ...
Even though the structural determinants of the binding are not known, it is generally accepted that the interaction of the non-substrate ligands with the enzyme restricts or alters the conformational dynamics of the enzyme, resulting in inhibition. In the case of the DM96 inhibitor, the strong ...