Fig. 3: LONP1 in the substrate-bound conformation contains an inactive protease site. a Surface representation of substrate-bound LONP1 showing a break in the protease domains between the highest subunit, ATP1, and its neighboring subunit, ATP2, highlighted using a dashed box. b The protease ...
Video S1. Super-resolution live cell imaging of mitochondrial division and fusion events, related to Figures 1E and 1M Video S2. Confocal live cell imaging of MTFP1-enriched IMM subdomains, related to Figure 2C Video S3. Confocal live cell imaging of MTFP1-enriched mitochondria, related to ...
Regulated intramembrane proteolysis of the amyloid precursor protein (APP) and its homologs, the APP like proteins APLP1 and APLP2, is typically a two-step process, which is initiated by ectodomain-shedding of the substrates by α- or β-secretases. Grow
However, it has also been shown that xIAP, rather than cIAP1 and cIAP2, is the critical target of BV6 in Fas-mediated apoptosis [44, 46]. Strikingly, we observed that LCL85 also sensitizes tumor cells to Fas-mediated apoptosis through inducing proteasomal degradation of xIAP. LCL85 ...
mode%3a%20wrap%3b%22%3e%3cstrong%3eshop%20now%20%26gt%3b%3c%2fstrong%3e%3c%2fa%3e%3c%2fp%3e","en":""},"id":"pageae5b2e5f-1d92-4bd3-bc8f-fde5bbba09f5"},"mandtabinfo":{"t_id":"pageb3744c0c-0db1-4f13-a506-e49cdb2b0a83","language":{"en_ie":"%3cp%3e%3cspan%...
j1AmbSYTE09slMReom9k0j7EkrFzdLKOsiiPiIfoQTHag3lX0FSTbMAfBZ3//+Olb7ih2CWJa7Um ZkfMgVINdVOUbLA5qcR2NStJ1c0xh4VfSBSsrMFLGTsTWdOoULKyyHUkiQ6jZBZWlqPhY4ZIQg1Y strkzCjluPbybX8oV7e1YvZGslYzydalWnSbVE2tb6FSqWNSq8Oat5Mcp91ZrGn4BUtBK93MMWiO sY2goYndbmI9c5wZ+a4Mv2CtVmxE4pekrTnEhnU...
%3cstrong%3eshop%20now%20%26gt%3b%3c%2fstrong%3e%3c%2fa%3e%3c%2fp%3e","en":"%3cp%3e%3cstrong%20style%3d%22text-wrap-mode%3a%20wrap%3b%22%3e%3c%2fstrong%3e%3cstrong%20style%3d%22text-wrap-mode%3a%20wrap%3b%22%3etrade%20in%20offer%3c%2fstrong%3e%3cstrong%20style%3d%22text-...
The kinesin-6 or mitotic kinesin (MKLP) family comprises three members in human cells: MKLP1 (KIF23), MKLP2 (KIF20A), and MPP1 (KIF20B). All three members have been characterised primarily because of their role in cell division, where they contribute to
释放另一个包含与p1相同地址的指针p2后,指针p1是否可以访问? 首先,结构定义似乎有误。我想你是说 typedef struct Class{ int data; struct Class *next;}key; 这次任务之后 newclass2 = newclass; 这两个指针指向同一个动态分配的内存。 然后指针newclass被重新分配为NULL newclass = NULL; 因此,为空指针调用...
As designed, TGP3 and TGP2 were eluted earlier than the free TGP (Fig. S4d). Next, we performed the coupled reaction. Consistent with the design, a peak with similar Ve of free TGP, which was presumed to be from the product (TGP0) of the coupled reaction (Fig. 1a), emerged in ...