P-糖蛋白(P-gp/ABCB1)是一类典型的多药耐药转运蛋白,可识别和促进肿瘤细胞的药物外排,限制了药物的疗效。迄今为止,具有靶向PI3K P110α和P110β以及抑制P-gp介导的肿瘤多药耐药的纳米药物系统尚未见报道。中国科学院福建物质结构研究所在逆转肿瘤细胞多药耐药研究中获进展。°福建物构所逆转肿瘤细胞多药耐药研究...
Human permeability glycoprotein,P-gp/ABCB1 ELISA Kit 英文别名: Human permeability glycoprotein,P-gp/ABCB1 ELISA Kit 中文名: 人P糖蛋白/渗透性糖蛋白(P-GP/ABCB1)ELISA KIT 中文别名: 人P糖蛋白/渗透性糖蛋白(P-GP/ABCB1)酶联免疫试剂盒;人P糖蛋白/渗透性糖蛋白(P-GP/ABCB1)ELISA KIT ...
产品规格:1mL(10mM)|5mg|10mg|50mg|100mg Dofequidar延胡索酸盐(MS-209延胡索酸盐)是喹啉化合物,能抑制ABCB1/P-gp,ABCC1/MDR-相关蛋白1。 注:本品仅可用于科研实验,严禁用于临床医疗及其他用途! CAS号:153653-30-6 别名:MS-209 纯度:99.66%
产品名称:ABCB1/P-gp/ABCC1/MDR-相关蛋白1抑制剂(Dofequidar fumarate) 英文名称:Dofequidar fumarate 产品货号:M01509 产品规格:1mL(10mM)|5mg|10mg|50mg|100mg Dofequidar延胡索酸盐(MS-209延胡索酸盐)是喹啉化合物,能抑制ABCB1/P-gp,ABCC1/MDR-相关蛋白1。
Here we present data on molecular identification of ABC efflux transporter - P-glycoprotein (P-gp/Abcb1), as a representative of MXR phenotype, in soil organism - earthworm *Eisenia fetida*. Partial cDNA sequence of *Abcb1 * was identified and its overall identity with ABCB1 homologues of ...
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ABCB1/P-gp/ABCC1/MDR-相关蛋白1抑制剂 英文名称: Dofequidar fumarate 总访问: 405 国产/进口: 国产 半年访问: 7 产地/品牌: 百奥莱博 产品类别: 细胞生物学试剂 规格: 153653-30-6 最后更新: 2024-11-4 货号: M01509 CAS 号: 153653-30-6 参考报价: 立即询价 电话咨询 ...
The hypothesis that allelic variation in the multidrug resistance-1 (MDR1 or ABCB1) gene encoding the P-glycoprotein (P-gp) blood-brain barrier efflux pump is associated with remission and side effects was tested in chronic major depression patients treated with P-gp substrates. In 83 patients...
家族1抗体(ATP-binding cassette sub-family B member 1，ABCB1)基因编码的P-糖蛋白(P-glycoprotein，P-gp)介导的人结肠癌耐奥沙利铂细胞株HCT-116/L-OHP细胞多药耐药性的调控作用。方法：将PI3K特异性抑 制剂LY294002(20 μmol/L)处理人结肠癌HCT-116/L-OHP细胞2 h后，用细胞计数试剂盒-8(cell ...
ABCB1, also called MDR1 or P-glycoprotein, exports various hydrophobic compounds and plays an essential role as a protective physiological barrier in several organs, including the brain, testis, and placenta. However, little is known about the structural mechanisms that allow ABCB1 to recognize hyd...