The induction of p-S65-Ub in primary cells suggests a significant role of p-S65-Ub also in neurons. Consistent with a marker for damaged mitochondria that are undergoing mitophagy, we find anti-p-S65-Ub immunoreactive granules that partially colocalize with mitochondria, lysosomes and ubiquitin ...
Using novel polyclonal antibodies, we find that p-S65-Ub specifically accumulates on damaged mitochondria. Phosphorylation of ubiquitin on serine 65 depends on the activity of PINK1 and the signal is vastly amplified by the activity of the E3 ubiquitin ligase PARK2/Parkin in a feed-forward loop....
Mutations in PINK1 and PARKIN are the most common causes of recessive early-onset Parkinson’s disease (EOPD). Together, the mitochondrial ubiquitin (Ub) kinase PINK1 and the cytosolic E3 Ub ligase PARKIN direct a complex regulated, sequential mitochondr
Sommer-Technik UB1816ST 1 cenbre 3011424 BAHR ELK60 desoutter 33923 OPTIMA SPANNTECHNIK OSV8800KN.X=144STROKE=475 ETH 1275 DRW-K-10.0 desoutter 575.105 BD sensors DMP331P 500-1602-1-3-100-Z61-112-200,0-16bar,G1/2 SOMMER索玛 FS14A-25V TURCK 3083542;SLPE14-550P8;909 FANUC A06B...
fmXPTS5uBH989d84993v+bxhV+zfZxpapYrNabe9obdinm+2iFocNGg6dGrI/VA23qde+VE/4SbXwjWr6S8vCGW22Hq20fnWHRRqAh0OXenSOcx5SPTynMve2Qjk01K+vVbfd/LdbZXtKvf6MzmqJ3as6ttcO6QbuVeA+WA13gp99N6xPbHDr+/1ZrkfTuxt2UuWStDKMa2nYiO9V9YUD2A4NWwv7BOu3NKzLrN/j/Xuw/3B/Eg7DEf73mF/DbuM/8hHuJ/...
+l3Ux3d49ZXXjUbhrEuTc7ZyS03szmlGcyY7cHnieE38/CnkgayLkvVMDHwpvaRstmtjxziO5oo0WkfenIgU8WXyGGxqa1hSMr4HVopMVodtmZfHaEviOeOzx1WWNWYpWWTxf1SkqLuaw5IULqsdsz6YcFmPLLHtl1nZa5NZzRO4GRFkWvh2VeDstVchj1x/+7uo5oe0+1fI6kjr1X98QWF9+G9kV5ZzfuyzL/K9n/g01/YWD/3+34jxpgewRVvz0t0TfuLF1/jt738...
We read every piece of feedback, and take your input very seriously. Include my email address so I can be contacted Cancel Submit feedback Saved searches Use saved searches to filter your results more quickly Cancel Create saved search Sign in Sign up Reseting focus {...
Shanghai Huishuo Trade Co.,Ltd.上海徽烁贸易有限公司专业致力于欧美工控备件进口,主要服务的行业是钢铁,石化,造纸,能源,港口,包装,电力,船舶,采矿,食品,饲料等;并与这些行业大部分的大型企业建立起直接或间接的合作模式。徽烁凭借拥有一支高素质专业人才从事贸易多年,积累了众多优势渠道,与德国、意大利、法国、英国...
WAYCONPL82-3 优势品牌HUBNERHOG10D10241Ub=+9/30V HYDAC-9244P4130-25U *BENDERB911743 MOOGHZR18D3 RKP063SM28H1Y00 RKP063SM28H1Y00D954Z8017-10 5分钟报价SCHUNKTCU-XY-125-3-OV-Z-1250324823 SCHUNK PZN-plus125-2-IS-V39303643 Magnet-Schultz电磁阀XBKK032K54F01=24V100%ED0.315AS0.8MM ...
染城亘古影院官网(www.fshaocheng.com),【会员在线观看】为您提供2025年03月最新仙侠传奇小说等, 93万+高清影视,染城亘古影院专门为百度、夸克、神马定制播放器,同时对主流的苹果IOS,华为、努比亚、魅族、红米等安卓手机系统及品牌做特殊支持,在线流畅的观看高清影视作