Journal of Biological ChemistryHill, A.V. 1921. The interactions of oxygen, acid, and CO2 in blood. J. Biol. Chem. Ii:359-364The interactions of oxygen, acid and CO2in blood. A. V. Hill. Journal of Biological Chemistry . 1922
Also in the transport of oxygen in the body binding to iron plays a role. Iron is an intricate part of the protein hemoglobin which is the transporter for oxygen in red blood cells from lungs to the mitochondria. Heme (as part of hemoglobin) is a specific molecular structure that holds ...
the effect of CO2 on oxygen affinity and Bohr effect in red cell suspensions and dilute (1.3 mM Hb4) and concentrated (5 mM Hb4) hemoglobin solutions at 37 degrees C and b) CO2 binding curves of deoxygenated and oxygenated whole blood and hemoglobin solutions, respectively, at the same tem...
BACKGROUND AND PURPOSE: Impaired cerebrovascular reserve capacity (CVC) is a risk factor for ischemic events in patients with high-grade carotid stenosis and occlusion. In this study, the CVC in response to a CO2 challenge was evaluated with blood oxygen level-dependent (BOLD) MRI and the resul...
The oxygen dissociation curve, showing PaO2vs. SaO2and PaO2vs. oxygen content for two different hemoglobin values. P50is the PaO2at which hemoglobin is 50% saturated with oxygen; normal value is 27 mm Hg. (X represents blood gas values of a case presented in Chapter 6). ...
Hypoxia due to carbon monoxide poisoning is due to the higher relative affinity of hemoglobin in red blood cells to CO over O2, resulting in insufficient O2 delivery to metabolizing tissues, with deleterious effects on the heart and the central nervous system (CNS) being most problematic. The ...
Cerebral blood flow (CBF) and cerebral metabolic rate of oxygen ... JB Madsen,GE Cold,ES Hansen,... - 《Anesthesiology》 被引量: 102发表: 1987年 Effects of indomethacin on intracranial pressure, cerebral perfusion pressure and CO2 reactivity during propofol/fentanil anaesthesia in patients ...
PtCO2 The mean (SD) change in PtCO2 after 35 min was 3.4 (1.9) mmHg in the oxygen group (n = 45), compared to 0.1 (1.4) mmHg in the air group (n = 44). The difference (95% CI) in PtCO2 for oxygen compared to air-driven nebulisations after 35 min was 3.3 mmHg (...
Secondary variables were: fraction of inspired oxygen (FIO2), oxygen saturation (SpO2), etCO2, systolic and mean blood pressure (BP), and heart rate (HR); these variables were analyzed for their association with drop in rScO2 to below baseline (%drop_rScO2). Results The incidence of AE ...
Hypoxia due to carbon monoxide poisoning is due to the higher relative affinity of hemoglobin in red blood cells to CO over O2, resulting in insufficient O2 delivery to metabolizing tissues, with deleterious effects on the heart and the central nervous system (CNS) being most problematic. The ...