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The main driver of the observed variations in DO is likely to be periodic melt-freeze cycles. We conclude that automated sensing techniques, such as those described here, when used in conjunction with physical measurements, have great potential for high-resolution monitoring of the factors that ...
Thus, when we screened human colorectal cancer driver genes, mutations were non-selectively distributed throughout the genome of tumors from Gpx4+/Δmye mice yet found at a much higher frequency when compared with control tumors (Figure 2L). These included Apc, Kras, Smad4, Trp53, Braf, ...
Differential expression and binding of such factors, however, could remain a driver of the hyper-reactive, pro-inflammatory nature of human HD PSC-derived microglia. Taken together, then, the data herein are consistent with a model in which mutant HTT promotes the expression of genes encoding ...
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Additionally, AKT plays as a critical driver of the tumor glycolytic phenotype and triggers ATP generation via multiple mechanisms to gain the bioenergetic capacity and responds to cancer growth. Moreover, the AKT modulates the metabolic alteration by activating transcription factors such as HIF-1, ...
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